A novel LCMSMS method for quantitative measurement of short-chain fatty acids in human stool derivatized with 12C-and 13C-labelled aniline JCY Chan, DYQ Kioh, GC Yap, BW Lee, ECY Chan Journal of pharmaceutical and biomedical analysis 138, 43-53, 2017 | 80 | 2017 |
A compromised developmental trajectory of the infant gut microbiome and metabolome in atopic eczema LDH Ta, JCY Chan, GC Yap, RW Purbojati, DI Drautz-Moses, YM Koh, ... Gut microbes 12 (1), 1801964, 2020 | 65 | 2020 |
Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation CY Chan, LS New, HK Ho, ECY Chan Toxicology letters 206 (3), 314-324, 2011 | 32 | 2011 |
Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib HK Ho, JCY Chan, KD Hardy, ECY Chan Drug metabolism reviews 47 (1), 21-28, 2015 | 29 | 2015 |
Reactive metabolite-induced protein glutathionylation: a potentially novel mechanism underlying acetaminophen hepatotoxicity JCY Chan, ACK Soh, DYQ Kioh, J Li, C Verma, SK Koh, RW Beuerman, ... Molecular & Cellular Proteomics 17 (10), 2034-2050, 2018 | 19 | 2018 |
In Silico and in Vitro Interactions between Short Chain Fatty Acids and Human Histone Deacetylases RH Ho, JCY Chan, H Fan, DYQ Kioh, BW Lee, ECY Chan Biochemistry 56 (36), 4871-4878, 2017 | 18 | 2017 |
The isotope‐coded affinity tag method for quantitative protein profile comparison and relative quantitation of cysteine redox modifications JCY Chan, L Zhou, ECY Chan Current Protocols in Protein Science 82 (1), 23.2. 1-23.2. 19, 2015 | 15 | 2015 |
Bottom-up physiologically-based biokinetic modelling as an alternative to animal testing JCY Chan, SPF Tan, Z Upton, ECY Chan ALTEX-Alternatives to animal experimentation 36 (4), 597-612, 2019 | 14 | 2019 |
Increased Protein S-Glutathionylation in Leber’s Hereditary Optic Neuropathy (LHON) L Zhou, JCY Chan, S Chupin, N Gueguen, V Desquiret-Dumas, SK Koh, ... International Journal of Molecular Sciences 21 (8), 3027, 2020 | 8 | 2020 |
Physiologically‐Based Pharmacokinetic Modeling to Predict the Clinical Efficacy of the Coadministration of Lopinavir and Ritonavir against SARS‐CoV‐2 A Thakur, SPF Tan, JCY Chan Clinical Pharmacology & Therapeutics 108 (6), 1176-1184, 2020 | 7 | 2020 |
Synergistic disruption of ERα/HER2 crosstalk by endoxifen and lapatinib in breast cancer cells JCY Chan, PS Ong, P Lim, PXL Teng, ECY Chan Cancer chemotherapy and pharmacology 79, 117-130, 2017 | 4 | 2017 |
Predicting human tissue exposures to xenobiotics using a bottom-up physiologically-based biokinetic model SPF Tan, ECY Chan, JCY Chan ALTEX-Alternatives to animal experimentation 38 (2), 253-268, 2021 | 2 | 2021 |
1476 Monitoring biomarkers of diabetic foot ulcers: Discovery proteomics from a prospective longitudinal study in an Asian population S Lee, AFB Afandi, H Tay, R Navasankari, A Karkhanis, JC Chan, Z Upton, ... Journal of Investigative Dermatology 143 (5), S253, 2023 | | 2023 |