James Whisstock
James Whisstock
Monash University, ARC Centre of Excellence in Advanced Molecular Imaging, EMBL Australia
Zweryfikowany adres z monash.edu
TytułCytowane przezRok
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins evolution, mechanism of inhibition, novel functions, and a revised nomenclature
GA Silverman, PI Bird, RW Carrell, FC Church, PB Coughlin, PGW Gettins, ...
Journal of Biological Chemistry 276 (36), 33293-33296, 2001
Prediction of protein function from protein sequence and structure
JC Whisstock, AM Lesk
Quarterly reviews of biophysics 36 (3), 307-340, 2003
Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function
JA Irving, RN Pike, AM Lesk, JC Whisstock
Genome research 10 (12), 1845-1864, 2000
MUSTANG: a multiple structural alignment algorithm
AS Konagurthu, JC Whisstock, PJ Stuckey, AM Lesk
Proteins: Structure, Function, and Bioinformatics 64 (3), 559-574, 2006
An overview of the serpin superfamily
RHP Law, Q Zhang, S McGowan, AM Buckle, GA Silverman, W Wong, ...
Genome biology 7 (5), 216, 2006
Perforin and granzymes: function, dysfunction and human pathology
I Voskoboinik, JC Whisstock, JA Trapani
Nature Reviews Immunology 15 (6), 388-400, 2015
A structural basis for the selection of dominant αβ T cell receptors in antiviral immunity
L Kjer-Nielsen, CS Clements, AW Purcell, AG Brooks, JC Whisstock, ...
Immunity 18 (1), 53-64, 2003
AB 5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP
AW Paton, T Beddoe, CM Thorpe, JC Whisstock, MCJ Wilce, J Rossjohn, ...
Nature 443 (7111), 548-552, 2006
The structural basis for membrane binding and pore formation by lymphocyte perforin
RHP Law, N Lukoyanova, I Voskoboinik, TT Caradoc-Davies, K Baran, ...
Nature 468 (7322), 447-451, 2010
T cell receptor recognition of a'super-bulged'major histocompatibility complex class I–bound peptide
FE Tynan, SR Burrows, AM Buckle, CS Clements, NA Borg, JJ Miles, ...
Nature immunology 6 (11), 1114-1122, 2005
A common fold mediates vertebrate defense and bacterial attack
CJ Rosado, AM Buckle, RHP Law, RE Butcher, WT Kan, CH Bird, K Ung, ...
Science 317 (5844), 1548-1551, 2007
Conservation within the myosin motor domain: implications for structure and function
MJTV Cope, J Whisstock, I Rayment, J Kendrick-Jones
Structure 4 (8), 969-987, 1996
Glycoprotein Ib–IX–V
RK Andrews, EE Gardiner, Y Shen, JC Whisstock, MC Berndt
The international journal of biochemistry & cell biology 35 (8), 1170-1174, 2003
The MACPF/CDC family of pore‐forming toxins
CJ Rosado, S Kondos, TE Bull, MJ Kuiper, RHP Law, AM Buckle, ...
Cellular microbiology 10 (9), 1765-1774, 2008
An atlas of serpin conformations
J Whisstock, R Skinner, AM Lesk
Trends in biochemical sciences 23 (2), 63-67, 1998
The 2.6 Å structure of antithrombin indicates a conformational change at the heparin binding site
R Skinner, JP Abrahams, JC Whisstock, AM Lesk, RW Carrell, ...
Journal of molecular biology 266 (3), 601-609, 1997
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
CA Nold-Petry, CY Lo, I Rudloff, KD Elgass, S Li, MP Gantier, ...
Nature immunology 16 (4), 354, 2015
The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-κB p65
HJ Newton, JS Pearson, L Badea, M Kelly, M Lucas, G Holloway, ...
PLoS pathogens 6 (5), 2010
Perforin: structure, function, and role in human immunopathology
I Voskoboinik, MA Dunstone, K Baran, JC Whisstock, JA Trapani
Immunological reviews 235 (1), 35-54, 2010
Functional insights from the distribution and role of homopeptide repeat-containing proteins
NG Faux, SP Bottomley, AM Lesk, JA Irving, JR Morrison, ...
Genome research 15 (4), 537-551, 2005
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