| Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism C Lerin, AB Goldfine, T Boes, M Liu, S Kasif, JM Dreyfuss, ... Molecular metabolism 5 (10), 926-936, 2016 | 141 | 2016 |
| The Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway in Pulmonary Arterial Hypertension J Chen, H Tang, JR Sysol, L Moreno-Vinasco, KM Shioura, T Chen, ... Am J Respir Crit Care Med 190 (9), 1032-1043, 2014 | 136 | 2014 |
| Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia I Manoli, JR Sysol, L Li, P Houillier, C Garone, C Wang, PM Zerfas, ... Proceedings of the National Academy of Sciences 110 (33), 13552-13557, 2013 | 126 | 2013 |
| Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria JL Sloan, JJ Johnston, I Manoli, RJ Chandler, C Krause, ... Nature Genetics 43 (9), 883-886, 2011 | 119 | 2011 |
| Deficiency of Akt1, but not Akt2, Attenuates the Development of Pulmonary Hypertension H Tang, J Chen, DR Fraidenburg, S Song, JR Sysol, AR Drennan, ... American Journal of Physiology-Lung Cellular and Molecular Physiology …, 2014 | 86 | 2014 |
| Nicotinamide phosphoribosyltransferase promotes pulmonary vascular remodeling and is a therapeutic target in pulmonary arterial hypertension J Chen, JR Sysol, S Singla, S Zhao, A Yamamura, D Valdez-Jasso, ... Circulation 135 (16), 1532-1546, 2017 | 66 | 2017 |
| FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia I Manoli, JR Sysol, MW Epping, L Li, C Wang, JL Sloan, A Pass, J Gagné, ... JCI insight 3 (23), 2018 | 57 | 2018 |
| Hemin causes lung microvascular endothelial barrier dysfunction by necroptotic cell death S Singla, JR Sysol, B Dille, N Jones, J Chen, RF Machado American journal of respiratory cell and molecular biology 57 (3), 307-314, 2017 | 49 | 2017 |
| PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation JR Sysol, V Natarajan, RF Machado American Journal of Physiology-Cell Physiology 310 (11), C983-C992, 2016 | 48 | 2016 |
| Classification and pathophysiology of pulmonary hypertension JR Sysol, RF Machado Continuing Cardiology Education 4 (1), 2-12, 2018 | 47 | 2018 |
| Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 JR Sysol, J Chen, S Singla, S Zhao, S Comhair, V Natarajan, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (3 …, 2018 | 35 | 2018 |
| Gene therapy in a murine model of methylmalonic acidemia using rAAV9-mediated gene delivery JS Sénac, RJ Chandler, JR Sysol, L Li, CP Venditti Gene Therapy 19 (4), 385-391, 2011 | 32 | 2011 |
| Progressive glomerular and tubular damage in sickle cell trait and sickle cell anemia mouse models SL Saraf, JR Sysol, A Susma, S Setty, X Zhang, KP Gudehithlu, ... Translational Research 197, 1-11, 2018 | 16 | 2018 |
| Loss of lung WWOX expression causes neutrophilic inflammation S Singla, J Chen, S Sethuraman, JR Sysol, A Gampa, S Zhao, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (6 …, 2017 | 16 | 2017 |
| Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease JD Duarte, AA Desai, JR Sysol, T Abbasi, AR Patel, RM Lang, A Gupta, ... PLoS One 11 (9), e0163013, 2016 | 13 | 2016 |
| ID: 54: CUTANEOUS MUCORMYCOSIS IN A PATIENT WITH CHRONIC LYMPHOCYTIC LEUKEMIA: A PHARMACOLOGICAL DILEMMA CEF Castro Journal of Investigative Medicine 64 (4), 956-957, 2016 | 8 | 2016 |
| Sickle cell disease and acute chest syndrome: epidemiology, diagnosis, management, outcomes JR Sysol, R Machado Hematologic abnormalities and acute lung syndromes, 67-87, 2017 | 6 | 2017 |
| Sphingosine kinase 1 deficiency in smooth muscle cells protects against hypoxia-mediated pulmonary hypertension via YAP1 signaling J Chen, A Lockett, S Zhao, LS Huang, Y Wang, W Wu, M Tang, S Haider, ... International journal of molecular sciences 23 (23), 14516, 2022 | 3 | 2022 |
| Cortactin loss protects against hemin-induced acute lung injury in sickle cell disease NM Jones, JR Sysol, S Singla, P Smith, GE Sandusky, H Wang, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 322 (6 …, 2022 | 3 | 2022 |
| 725 Ye RD, Bonini MG, Minshall RD, Garcia JG, Machado RF, Makino A, and Yuan JX. 726 Deficiency of Akt1, but not Akt2, Attenuates the Development of Pulmonary Hypertension H Tang, J Chen, DR Fraidenburg, S Song, JR Sysol, AR Drennan, ... Am 727 J Physiol Lung Cell Mol Physiol, 2014 | 3 | 2014 |
