| Development of Novel, Value-Based, Digital Endpoints for Clinical Trials: A Structured Approach Toward Fit-for-Purpose Validation MD Kruizinga, FE Stuurman, V Exadaktylos, RJ Doll, DT Stephenson, ... Pharmacological Reviews 72 (4), 899-909, 2020 | 41 | 2020 |
| Quantification of tremor using consumer product accelerometry is feasible in patients with essential tremor and Parkinson’s disease: a comparative study EMJ van Brummelen, D Ziagkos, WMI de Boon, EP Hart, RJ Doll, ... Journal of Clinical Movement Disorders 7, 1-11, 2020 | 36 | 2020 |
| Tracking of nociceptive thresholds using adaptive psychophysical methods RJ Doll, JR Buitenweg, HGE Meijer, PH Veltink Behavior Research Methods 46, 55-66, 2014 | 36 | 2014 |
| Observation of time-dependent psychophysical functions and accounting for threshold drifts RJ Doll, PH Veltink, JR Buitenweg Attention, Perception, & Psychophysics 77, 1440-1447, 2015 | 32 | 2015 |
| Effect of temporal stimulus properties on the nociceptive detection probability using intra-epidermal electrical stimulation RJ Doll, ACA Maten, SPG Spaan, PH Veltink, JR Buitenweg Experimental brain research 234, 219-227, 2016 | 28 | 2016 |
| Simultaneous tracking of psychophysical detection thresholds and evoked potentials to study nociceptive processing B van den Berg, RJ Doll, ALH Mentink, PS Siebenga, GJ Groeneveld, ... Behavior research methods 52, 1617-1628, 2020 | 27 | 2020 |
| Responsiveness of electrical nociceptive detection thresholds to capsaicin (8%)-induced changes in nociceptive processing RJ Doll, G van Amerongen, JL Hay, GJ Groeneveld, PH Veltink, ... Experimental Brain Research 234, 2505-2514, 2016 | 26 | 2016 |
| Safety, pharmacokinetics and exploratory pro-cognitive effects of HTL0018318, a selective M1 receptor agonist, in healthy younger adult and elderly subjects: a … C Bakker, T Tasker, J Liptrot, EP Hart, ES Klaassen, RJ Doll, GA Brown, ... Alzheimer's Research & Therapy 13, 1-19, 2021 | 15 | 2021 |
| Finding suitable clinical endpoints for a potential treatment of a rare genetic disease: the case of ARID1B MD Kruizinga, RGJA Zuiker, E Sali, ML de Kam, RJ Doll, GJ Groeneveld, ... Neurotherapeutics 17 (3), 1300-1310, 2020 | 13 | 2020 |
| Cardiac age detected by machine learning applied to the surface ECG of healthy subjects: Creation of a benchmark HEC van der Wall, GJ Hassing, RJ Doll, GJP van Westen, AF Cohen, ... Journal of Electrocardiology 72, 49-55, 2022 | 10 | 2022 |
| Computational modeling of Adelta-fiber-mediated nociceptive detection of electrocutaneous stimulation H Yang, HGE Meijer, RJ Doll, JR Buitenweg, SA van Gils Biological cybernetics 109 (4), 479-491, 2015 | 10 | 2015 |
| Development and technical validation of a smartphone-based pediatric cough detection algorithm MD Kruizinga, A Zhuparris, E Dessing, FJ Krol, AJ Sprij, RJ Doll, ... Pediatric pulmonology 57 (3), 761-767, 2022 | 9 | 2022 |
| Simultaneous measurement of intra-epidermal electric detection thresholds and evoked potentials for observation of nociceptive processing following sleep deprivation B van den Berg, HJ Hijma, I Koopmans, RJ Doll, RGJA Zuiker, ... Experimental brain research 240 (2), 631-649, 2022 | 9 | 2022 |
| The use of machine learning improves the assessment of drug-induced driving behaviour HEC van der Wall, RJ Doll, GJP van Westen, I Koopmans, RG Zuiker, ... Accident Analysis & Prevention 148, 105822, 2020 | 9 | 2020 |
| A computerized test battery to study pharmacodynamic effects on the central nervous system of cholinergic drugs in early phase drug development EP Hart, R Alvarez-Jimenez, E Davidse, RJ Doll, AF Cohen, ... JoVE (Journal of Visualized Experiments), e56569, 2019 | 9 | 2019 |
| Development and technical validation of a smartphone-based cry detection algorithm A ZhuParris, MD Kruizinga, M Gent, E Dessing, V Exadaktylos, RJ Doll, ... Frontiers in pediatrics 9, 651356, 2021 | 8 | 2021 |
| Touchscreen-based finger tapping: Repeatability and configuration effects on tapping performance S Makai-Bölöni, E Thijssen, EMJ van Brummelen, GJ Groeneveld, RJ Doll PloS one 16 (12), e0260783, 2021 | 7 | 2021 |
| Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double‐blind, placebo‐controlled, cross‐over study TQ Ruijs, JAAC Heuberger, AA de Goede, D Ziagkos, ME Otto, RJ Doll, ... British Journal of Clinical Pharmacology 88 (6), 2926-2937, 2022 | 6 | 2022 |
| Detection of Clenbuterol-Induced Changes in Heart Rate Using At-Home Recorded Smartwatch Data: Randomized Controlled Trial WO Elzinga, S Prins, LGJM Borghans, P Gal, GA Vargas, GJ Groeneveld, ... JMIR Formative Research 5 (12), e31890, 2021 | 6 | 2021 |
| A Placebo‐Controlled Study to Assess the Sensitivity of Finger Tapping to Medication Effects in Parkinson's Disease E Thijssen, S Makai‐Bölöni, E van Brummelen, J den Heijer, Y Yavuz, ... Movement disorders clinical practice 9 (8), 1074-1084, 2022 | 5 | 2022 |
