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Stephin Vervoort
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Tumor immune evasion arises through loss of TNF sensitivity
CJ Kearney, SJ Vervoort, SJ Hogg, KM Ramsbottom, AJ Freeman, ...
Science immunology 3 (23), eaar3451, 2018
2902018
Inhibition of endosteal vascular niche remodeling rescues hematopoietic stem cell loss in AML
D Duarte, ED Hawkins, O Akinduro, H Ang, K De Filippo, IY Kong, ...
Cell stem cell 22 (1), 64-77. e6, 2018
2882018
BET-bromodomain inhibitors engage the host immune system and regulate expression of the immune checkpoint ligand PD-L1
SJ Hogg, SJ Vervoort, S Deswal, CJ Ott, J Li, LA Cluse, PA Beavis, ...
Cell reports 18 (9), 2162-2174, 2017
2712017
Modulation of glutamine metabolism by the PI (3) K–PKB–FOXO network regulates autophagy
KE Van Der Vos, P Eliasson, T Proikas-Cezanne, SJ Vervoort, ...
Nature cell biology 14 (8), 829-837, 2012
2642012
The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe?
SJ Vervoort, R van Boxtel, PJ Coffer
Oncogene 32 (29), 3397-3409, 2013
2272013
Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
J Lai, S Mardiana, IG House, K Sek, MA Henderson, L Giuffrida, ...
Nature immunology 21 (8), 914-926, 2020
1352020
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, S Offley, ...
Cell 184 (12), 3143-3162. e32, 2021
1152021
SOX4 mediates TGF-β-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition
SJ Vervoort, AR Lourenço, R van Boxtel, PJ Coffer
PloS one 8 (1), e53238, 2013
1112013
Inhibition of super-enhancer activity in autoinflammatory site-derived T cells reduces disease-associated gene expression
JGC Peeters, SJ Vervoort, SC Tan, G Mijnheer, S de Roock, SJ Vastert, ...
Cell reports 12 (12), 1986-1996, 2015
1042015
CDK13 cooperates with CDK12 to control global RNA polymerase II processivity
Z Fan, JR Devlin, SJ Hogg, MA Doyle, PF Harrison, I Todorovski, ...
Science advances 6 (18), eaaz5041, 2020
1032020
Natural killer cells suppress T cell-associated tumor immune evasion
AJ Freeman, SJ Vervoort, KM Ramsbottom, MJ Kelly, J Michie, L Pijpers, ...
Cell reports 28 (11), 2784-2794. e5, 2019
882019
Antagonism of IAPs enhances CAR T-cell efficacy
J Michie, PA Beavis, AJ Freeman, SJ Vervoort, KM Ramsbottom, ...
Cancer immunology research 7 (2), 183-192, 2019
732019
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
SJ Hogg, O Motorna, LA Cluse, TM Johanson, HD Coughlan, R Raviram, ...
Molecular cell 81 (10), 2183-2200. e13, 2021
722021
BET inhibition induces apoptosis in aggressive B-cell lymphoma via epigenetic regulation of BCL-2 family members
SJ Hogg, A Newbold, SJ Vervoort, LA Cluse, BP Martin, GP Gregory, ...
Molecular cancer therapeutics 15 (9), 2030-2041, 2016
722016
CDK4/6 inhibition promotes antitumor immunity through the induction of T-cell memory
EJ Lelliott, IY Kong, M Zethoven, KM Ramsbottom, LG Martelotto, ...
Cancer discovery 11 (10), 2582-2601, 2021
692021
Complexity and diversity of the mammalian sialome revealed by nidovirus virolectins
MA Langereis, MJG Bakkers, L Deng, V Padler-Karavani, SJ Vervoort, ...
Cell reports 11 (12), 1966-1978, 2015
672015
Targeting transcription cycles in cancer
SJ Vervoort, JR Devlin, N Kwiatkowski, M Teng, NS Gray, RW Johnstone
Nature Reviews Cancer 22 (1), 5-24, 2022
652022
IL-15 preconditioning augments CAR T cell responses to checkpoint blockade for improved treatment of solid tumors
L Giuffrida, K Sek, MA Henderson, IG House, J Lai, AXY Chen, KL Todd, ...
Molecular Therapy 28 (11), 2379-2393, 2020
642020
FOXP1 promotes embryonic neural stem cell differentiation by repressing Jagged1 expression
L Braccioli, SJ Vervoort, Y Adolfs, CJ Heijnen, O Basak, RJ Pasterkamp, ...
Stem cell reports 9 (5), 1530-1545, 2017
632017
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis
MJ Kelly, J So, AJ Rogers, G Gregory, J Li, M Zethoven, MD Gearhart, ...
Nature communications 10 (1), 1347, 2019
582019
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