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Haider H. Dar
Haider H. Dar
Zweryfikowany adres z pitt.edu
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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
VE Kagan, G Mao, F Qu, JPF Angeli, S Doll, CS Croix, HH Dar, B Liu, ...
Nature chemical biology 13 (1), 81-90, 2017
18622017
PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals
SE Wenzel, YY Tyurina, J Zhao, CMS Croix, HH Dar, G Mao, VA Tyurin, ...
Cell 171 (3), 628-641. e26, 2017
6692017
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death
AA Kapralov, Q Yang, HH Dar, YY Tyurina, TS Anthonymuthu, R Kim, ...
Nature chemical biology 16 (3), 278-290, 2020
3592020
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal
WY Sun, VA Tyurin, K Mikulska-Ruminska, IH Shrivastava, ...
Nature chemical biology 17 (4), 465-476, 2021
1942021
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O
N Mashtalir, S Daou, H Barbour, NN Sen, J Gagnon, I Hammond-Martel, ...
Molecular cell 54 (3), 392-406, 2014
1872014
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium
HH Dar, YY Tyurina, K Mikulska-Ruminska, I Shrivastava, HC Ting, ...
The Journal of clinical investigation 128 (10), 4639-4653, 2019
1732019
NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy
VE Kagan, J Jiang, Z Huang, YY Tyurina, C Desbourdes, ...
Cell Death & Differentiation 23 (7), 1140-1151, 2016
1732016
Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis
TS Anthonymuthu, YY Tyurina, WY Sun, K Mikulska-Ruminska, ...
Redox Biology 38, 101744, 2021
822021
Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity
K Balasubramanian, A Maeda, JS Lee, D Mohammadyani, HH Dar, ...
Science signaling 8 (395), ra95-ra95, 2015
792015
Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE
TS Anthonymuthu, EM Kenny, I Shrivastava, YY Tyurina, ZE Hier, HC Ting, ...
Journal of the American Chemical Society 140 (51), 17835-17839, 2018
722018
PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells
J Zhao, HH Dar, Y Deng, CM St. Croix, Z Li, Y Minami, IH Shrivastava, ...
Proceedings of the National Academy of Sciences 117 (25), 14376-14385, 2020
712020
Redox phospholipidomics of enzymatically generated oxygenated phospholipids as specific signals of programmed cell death
VE Kagan, YY Tyurina, WY Sun, II Vlasova, H Dar, VA Tyurin, ...
Free Radical Biology and Medicine 147, 231-241, 2020
552020
A new thiol-independent mechanism of epithelial host defense against Pseudomonas aeruginosa: iNOS/NO• sabotage of theft-ferroptosis
HH Dar, TS Anthonymuthu, LA Ponomareva, AB Souryavong, GV Shurin, ...
Redox Biology 45, 102045, 2021
512021
Redox (phospho) lipidomics of signaling in inflammation and programmed cell death
YY Tyurina, CM St. Croix, SC Watkins, AM Watson, MW Epperly, ...
Journal of leukocyte biology 106 (1), 57-81, 2019
402019
“Only a life lived for others is worth living”: redox signaling by oxygenated phospholipids in cell fate decisions
YY Tyurina, I Shrivastava, VA Tyurin, G Mao, HH Dar, S Watkins, ...
Antioxidants & redox signaling 29 (13), 1333-1358, 2018
342018
Intermolecular phosphotransfer is crucial for efficient catalytic activity of nucleoside diphosphate kinase
HH Dar, PK Chakraborti
Biochemical Journal 430 (3), 539-549, 2010
222010
Secretory nucleoside diphosphate kinases from both intra-and extracellular pathogenic bacteria are functionally indistinguishable
HH Dar, D Prasad, GC Varshney, PK Chakraborti
Microbiology 157 (11), 3024-3035, 2011
202011
P. aeruginosa augments irradiation injury via 15-lipoxygenase–catalyzed generation of 15-HpETE-PE and induction of theft-ferroptosis
HH Dar, MW Epperly, VA Tyurin, AA Amoscato, TS Anthonymuthu, ...
JCI insight 7 (4), 2022
192022
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death
AM Lamade, L Wu, HH Dar, HL Mentrup, IH Shrivastava, MW Epperly, ...
Redox Biology 50, 102232, 2022
172022
Nanoemitters and innate immunity: the role of surfactants and bio-coronas in myeloperoxidase-catalyzed oxidation of pristine single-walled carbon nanotubes
CF Chiu, HH Dar, AA Kapralov, RAS Robinson, VE Kagan, A Star
Nanoscale 9 (18), 5948-5956, 2017
112017
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