Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis VE Kagan, G Mao, F Qu, JPF Angeli, S Doll, CS Croix, HH Dar, B Liu, ... Nature chemical biology 13 (1), 81-90, 2017 | 1862 | 2017 |
PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals SE Wenzel, YY Tyurina, J Zhao, CMS Croix, HH Dar, G Mao, VA Tyurin, ... Cell 171 (3), 628-641. e26, 2017 | 669 | 2017 |
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death AA Kapralov, Q Yang, HH Dar, YY Tyurina, TS Anthonymuthu, R Kim, ... Nature chemical biology 16 (3), 278-290, 2020 | 359 | 2020 |
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal WY Sun, VA Tyurin, K Mikulska-Ruminska, IH Shrivastava, ... Nature chemical biology 17 (4), 465-476, 2021 | 194 | 2021 |
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O N Mashtalir, S Daou, H Barbour, NN Sen, J Gagnon, I Hammond-Martel, ... Molecular cell 54 (3), 392-406, 2014 | 187 | 2014 |
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium HH Dar, YY Tyurina, K Mikulska-Ruminska, I Shrivastava, HC Ting, ... The Journal of clinical investigation 128 (10), 4639-4653, 2019 | 173 | 2019 |
NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy VE Kagan, J Jiang, Z Huang, YY Tyurina, C Desbourdes, ... Cell Death & Differentiation 23 (7), 1140-1151, 2016 | 173 | 2016 |
Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis TS Anthonymuthu, YY Tyurina, WY Sun, K Mikulska-Ruminska, ... Redox Biology 38, 101744, 2021 | 82 | 2021 |
Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity K Balasubramanian, A Maeda, JS Lee, D Mohammadyani, HH Dar, ... Science signaling 8 (395), ra95-ra95, 2015 | 79 | 2015 |
Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE TS Anthonymuthu, EM Kenny, I Shrivastava, YY Tyurina, ZE Hier, HC Ting, ... Journal of the American Chemical Society 140 (51), 17835-17839, 2018 | 72 | 2018 |
PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells J Zhao, HH Dar, Y Deng, CM St. Croix, Z Li, Y Minami, IH Shrivastava, ... Proceedings of the National Academy of Sciences 117 (25), 14376-14385, 2020 | 71 | 2020 |
Redox phospholipidomics of enzymatically generated oxygenated phospholipids as specific signals of programmed cell death VE Kagan, YY Tyurina, WY Sun, II Vlasova, H Dar, VA Tyurin, ... Free Radical Biology and Medicine 147, 231-241, 2020 | 55 | 2020 |
A new thiol-independent mechanism of epithelial host defense against Pseudomonas aeruginosa: iNOS/NO• sabotage of theft-ferroptosis HH Dar, TS Anthonymuthu, LA Ponomareva, AB Souryavong, GV Shurin, ... Redox Biology 45, 102045, 2021 | 51 | 2021 |
Redox (phospho) lipidomics of signaling in inflammation and programmed cell death YY Tyurina, CM St. Croix, SC Watkins, AM Watson, MW Epperly, ... Journal of leukocyte biology 106 (1), 57-81, 2019 | 40 | 2019 |
“Only a life lived for others is worth living”: redox signaling by oxygenated phospholipids in cell fate decisions YY Tyurina, I Shrivastava, VA Tyurin, G Mao, HH Dar, S Watkins, ... Antioxidants & redox signaling 29 (13), 1333-1358, 2018 | 34 | 2018 |
Intermolecular phosphotransfer is crucial for efficient catalytic activity of nucleoside diphosphate kinase HH Dar, PK Chakraborti Biochemical Journal 430 (3), 539-549, 2010 | 22 | 2010 |
Secretory nucleoside diphosphate kinases from both intra-and extracellular pathogenic bacteria are functionally indistinguishable HH Dar, D Prasad, GC Varshney, PK Chakraborti Microbiology 157 (11), 3024-3035, 2011 | 20 | 2011 |
P. aeruginosa augments irradiation injury via 15-lipoxygenase–catalyzed generation of 15-HpETE-PE and induction of theft-ferroptosis HH Dar, MW Epperly, VA Tyurin, AA Amoscato, TS Anthonymuthu, ... JCI insight 7 (4), 2022 | 19 | 2022 |
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death AM Lamade, L Wu, HH Dar, HL Mentrup, IH Shrivastava, MW Epperly, ... Redox Biology 50, 102232, 2022 | 17 | 2022 |
Nanoemitters and innate immunity: the role of surfactants and bio-coronas in myeloperoxidase-catalyzed oxidation of pristine single-walled carbon nanotubes CF Chiu, HH Dar, AA Kapralov, RAS Robinson, VE Kagan, A Star Nanoscale 9 (18), 5948-5956, 2017 | 11 | 2017 |