Sean A. McKenna
Sean A. McKenna
Professor, Chemistry, University of Manitoba
Verified email at - Homepage
Cited by
Cited by
Dynamic light scattering: a practical guide and applications in biomedical sciences
J Stetefeld, SA McKenna, TR Patel
Biophysical reviews 8 (4), 409-427, 2016
Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail
KS Hamilton, MJ Ellison, KR Barber, RS Williams, JT Huzil, S McKenna, ...
Structure 9 (10), 897-904, 2001
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13
TF Moraes, RA Edwards, S McKenna, L Pastushok, W Xiao, JNM Glover, ...
Nature structural biology 8 (8), 669-673, 2001
Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A
PL Andersen, H Zhou, L Pastushok, T Moraes, S McKenna, B Ziola, ...
The Journal of cell biology 170 (5), 745-755, 2005
Noncovalent interaction between ubiquitin and the human DNA repair protein Mms2 is required for Ubc13-mediated polyubiquitination
S McKenna, L Spyracopoulos, T Moraes, L Pastushok, C Ptak, W Xiao, ...
Journal of Biological Chemistry 276 (43), 40120-40126, 2001
The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary
EP Booy, M Meier, N Okun, SK Novakowski, S Xiong, J Stetefeld, ...
Nucleic acids research 40 (9), 4110-4124, 2012
An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2· Ubc13: The structural basis for lysine 63 chain catalysis
S McKenna, T Moraes, L Pastushok, C Ptak, W Xiao, L Spyracopoulos, ...
Journal of Biological Chemistry 278 (15), 13151-13158, 2003
Rapid purification of RNAs using fast performance liquid chromatography (FPLC)
I Kim, SA Mckenna, EV Puglisi, JD Puglisi
Rna 13 (2), 289-294, 2007
Purification and characterization of transcribed RNAs using gel filtration chromatography
SA McKenna, I Kim, EV Puglisi, DA Lindhout, CE Aitken, RA Marshall, ...
Nature protocols 2 (12), 3270, 2007
The anti-hepatitis C agent nitazoxanide induces phosphorylation of eukaryotic initiation factor 2α via protein kinase activated by double-stranded RNA activation
M Elazar, M Liu, SA McKenna, P Liu, EA Gehrig, JD Puglisi, JF Rossignol, ...
Gastroenterology 137 (5), 1827-1835, 2009
Translational insensitivity to potent activation of PKR by HCV IRES RNA
T Shimoike, SA McKenna, DA Lindhout, JD Puglisi
Antiviral research 83 (3), 228-237, 2009
Uncoupling of RNA binding and PKR kinase activation by viral inhibitor RNAs
SA McKenna, I Kim, CW Liu, JD Puglisi
Journal of molecular biology 358 (5), 1270-1285, 2006
Viral dsRNA inhibitors prevent self-association and autophosphorylation of PKR
SA McKenna, DA Lindhout, T Shimoike, CE Aitken, JD Puglisi
Journal of molecular biology 372 (1), 103-113, 2007
Molecular framework for the activation of RNA-dependent protein kinase
SA McKenna, DA Lindhout, I Kim, CW Liu, VM Gelev, G Wagner, ...
Journal of Biological Chemistry 282 (15), 11474-11486, 2007
Adjuvants based on hybrid antibiotics overcome resistance in Pseudomonas aeruginosa and enhance fluoroquinolone efficacy
BK Gorityala, G Guchhait, DM Fernando, S Deo, SA McKenna, GG Zhanel, ...
Angewandte Chemie International Edition 55 (2), 555-559, 2016
The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1
EP Booy, R Howard, O Marushchak, EO Ariyo, M Meier, SK Novakowski, ...
Nucleic acids research 42 (5), 3346-3361, 2014
Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU)
M Meier, TR Patel, EP Booy, O Marushchak, N Okun, S Deo, R Howard, ...
Journal of Biological Chemistry 288 (49), 35014-35027, 2013
Energetics and specificity of interactions within Ub⊙ Uev⊙ Ubc13 human ubiquitin conjugation complexes
S McKenna, J Hu, T Moraes, W Xiao, MJ Ellison, L Spyracopoulos
Biochemistry 42 (26), 7922-7930, 2003
The long non-coding RNA BC200 (BCYRN1) is critical for cancer cell survival and proliferation
EP Booy, EKS McRae, A Koul, F Lin, SA McKenna
Molecular cancer 16 (1), 1-15, 2017
Human DDX21 binds and unwinds RNA guanine quadruplexes
EKS McRae, EP Booy, A Moya-Torres, P Ezzati, J Stetefeld, SA McKenna
Nucleic acids research 45 (11), 6656-6668, 2017
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