Jacques Neefjes
Jacques Neefjes
Hoogleraar cell biologie en immunologie, Leiden Universiteit
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Cited by
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Towards a systems understanding of MHC class I and MHC class II antigen presentation
J Neefjes, MLM Jongsma, P Paul, O Bakke
Nature reviews immunology 11 (12), 823-836, 2011
Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
EA Reits, JW Hodge, CA Herberts, TA Groothuis, M Chakraborty, ...
The Journal of experimental medicine 203 (5), 1259-1271, 2006
Empty MHC class I molecules come out in the cold
HG Ljunggren, NJ Stam, C Öhlén, JJ Neefjes, P Höglund, MT Heemels, ...
Nature 346 (6283), 476-480, 1990
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors
I Jordens, M Fernandez-Borja, M Marsman, S Dusseljee, L Janssen, ...
Current Biology 11 (21), 1680-1685, 2001
From fixed to FRAP: measuring protein mobility and activity in living cells
EAJ Reits, JJ Neefjes
Nature cell biology 3 (6), E145, 2001
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments
PJ Peters, JJ Neefjes, V Oorschot, HL Ploegh, HJ Geuze
Nature 349 (6311), 669-676, 1991
Present yourself! By MHC class I and MHC class II molecules
KL Rock, E Reits, J Neefjes
Trends in immunology 37 (11), 724-737, 2016
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Glued and late endosome positioning
N Rocha, C Kuijl, R Van Der Kant, L Janssen, D Houben, H Janssen, ...
Journal of Cell Biology 185 (7), 1209-1225, 2009
Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase
RA Gruters, JJ Neefjes, M Tersmette, REY de Goede, A Tulp, ...
Nature 330 (6143), 74-77, 1987
Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter
JJ Neefjes, F Momburg, GJ Hämmerling
Science 261 (5122), 769-771, 1993
E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro.
JF Leeuwenberg, EF Smeets, JJ Neefjes, MA Shaffer, T Cinek, ...
Immunology 77 (4), 543, 1992
Making sense of mass destruction: quantitating MHC class I antigen presentation
JW Yewdell, E Reits, J Neefjes
Nature Reviews Immunology 3 (12), 952-961, 2003
Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150Glued, ORP1L, and the receptor βlll spectrin
M Johansson, N Rocha, W Zwart, I Jordens, L Janssen, C Kuijl, ...
The Journal of cell biology 176 (4), 459-471, 2007
Cross-presentation by intercellular peptide transfer through gap junctions
J Neijssen, C Herberts, JW Drijfhout, E Reits, L Janssen, J Neefjes
Nature 434 (7029), 83-88, 2005
The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route
JJ Neefjes, V Stollorz, PJ Peters, HJ Geuze, HL Ploegh
Cell 61 (1), 171-183, 1990
The major substrates for TAP invivo are derived from newly synthesized proteins
EAJ Reits, JC Vos, M Gromme, J Neefjes
Nature 404 (6779), 774-778, 2000
Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro
TNM Schumacher, MT Heemels, JJ Neefjes, WM Kast, CJM Melief, ...
Cell 62 (3), 563-567, 1990
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling
S Huang, M Hölzel, T Knijnenburg, A Schlicker, P Roepman, U McDermott, ...
Cell 151 (5), 937-950, 2012
Mannose receptor‐mediated uptake of antigens strongly enhances HLA class II‐restricted antigen presentation by cultured dendritic cells
MCAA Tan, AM Mommaas, JW Drijfhout, R Jordens, JJM Onderwater, ...
European journal of immunology 27 (9), 2426-2435, 1997
Mice lacking the MHC class II-associated invariant chain
S Viville, J Neefjes, V Lotteau, A Dierich, M Lemeur, H Ploegh, C Benoist, ...
Cell 72 (4), 635-648, 1993
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