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John C Gensel
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Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
KA Kigerl, JC Gensel, DP Ankeny, JK Alexander, DJ Donnelly, ...
Journal of Neuroscience 29 (43), 13435-13444, 2009
23622009
Macrophage activation and its role in repair and pathology after spinal cord injury
JC Gensel, B Zhang
Brain research 1619, 1-11, 2015
7352015
Spinal cord injury scarring and inflammation: therapies targeting glial and inflammatory responses
MB Orr, JC Gensel
Neurotherapeutics 15, 541-553, 2018
4652018
Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury.
FAR Nielson JL, Paquette J, Liu AW, Guandique CF, Tovar CA, Inoue T, Irvine ...
Nat Commun 14 (6), 8581, 2015
388*2015
Behavioral and histological characterization of unilateral cervical spinal cord contusion injury in rats
JC Gensel, CA Tovar, FPT Hamers, RJ Deibert, MS Beattie, ...
Journal of neurotrauma 23 (1), 36-54, 2006
2862006
Immune activation promotes depression 1 month after diffuse brain injury: a role for primed microglia
AM Fenn, JC Gensel, Y Huang, PG Popovich, J Lifshitz, JP Godbout
Biological psychiatry 76 (7), 575-584, 2014
2802014
Cell death after spinal cord injury is exacerbated by rapid TNFα-induced trafficking of GluR2-lacking AMPARs to the plasma membrane
AR Ferguson, RN Christensen, JC Gensel, BA Miller, F Sun, EC Beattie, ...
Journal of Neuroscience 28 (44), 11391-11400, 2008
2672008
Macrophages promote axon regeneration with concurrent neurotoxicity
JC Gensel, S Nakamura, Z Guan, N van Rooijen, DP Ankeny, ...
Journal of Neuroscience 29 (12), 3956-3968, 2009
2472009
IL-4 signaling drives a unique arginase+/IL-1β+ microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after …
AM Fenn, JCE Hall, JC Gensel, PG Popovich, JP Godbout
Journal of Neuroscience 34 (26), 8904-8917, 2014
2182014
Microglia and macrophage metabolism in CNS injury and disease: The role of immunometabolism in neurodegeneration and neurotrauma
NA Devanney, AN Stewart, JC Gensel
Experimental neurology 329, 113310, 2020
1772020
Macrophages are necessary for epimorphic regeneration in African spiny mice
J Simkin, TR Gawriluk, JC Gensel, AW Seifert
Elife 6, e24623, 2017
1732017
Acute transplantation of glial-restricted precursor cells into spinal cord contusion injuries: survival, differentiation, and effects on lesion environment and axonal regeneration
CE Hill, C Proschel, M Noble, M Mayer-Proschel, JC Gensel, MS Beattie, ...
Experimental neurology 190 (2), 289-310, 2004
1672004
Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment
JC Gensel, TJ Kopper, B Zhang, MB Orr, WM Bailey
Scientific reports 7 (1), 40144, 2017
1552017
An efficient and reproducible method for quantifying macrophages in different experimental models of central nervous system pathology
DJ Donnelly, JC Gensel, DP Ankeny, N van Rooijen, PG Popovich
Journal of neuroscience methods 181 (1), 36-44, 2009
1462009
Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury
B Zhang, WM Bailey, KJ Braun, JC Gensel
Experimental neurology 273, 83-91, 2015
1262015
Large animal and primate models of spinal cord injury for the testing of novel therapies
BK Kwon, F Streijger, CE Hill, AJ Anderson, M Bacon, MS Beattie, ...
Experimental neurology 269, 154-168, 2015
1122015
Myelin as an inflammatory mediator: Myelin interactions with complement, macrophages, and microglia in spinal cord injury
TJ Kopper, JC Gensel
Journal of neuroscience research 96 (6), 969-977, 2018
1042018
Is neuroinflammation in the injured spinal cord different than in the brain? Examining intrinsic differences between the brain and spinal cord
B Zhang, JC Gensel
Experimental neurology 258, 112-120, 2014
1032014
Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury
B Zhang, WM Bailey, TJ Kopper, MB Orr, DJ Feola, JC Gensel
Journal of neuroinflammation 12 (1), 218, 2015
952015
Age increases reactive oxygen species production in macrophages and potentiates oxidative damage after spinal cord injury
B Zhang, WM Bailey, AL McVicar, JC Gensel
Neurobiology of Aging 47, 157-167, 2016
932016
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Prace 1–20