Petr Broz
Petr Broz
Associate Professor, Department of Biochemistry, University of Lausanne
Verified email at - Homepage
Cited by
Cited by
Inflammasomes: mechanism of assembly, regulation and signalling
P Broz, VM Dixit
Nature Reviews Immunology 16 (7), 407-420, 2016
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
P Broz, K Newton, M Lamkanfi, S Mariathasan, VM Dixit, DM Monack
Journal of Experimental Medicine 207 (8), 1745-1755, 2010
Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing
P Broz, J von Moltke, JW Jones, RE Vance, DM Monack
Cell host & microbe 8 (6), 471-483, 2010
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
JW Jones, N Kayagaki, P Broz, T Henry, K Newton, K O'Rourke, S Chan, ...
Proceedings of the National Academy of Sciences 107 (21), 9771-9776, 2010
Newly described pattern recognition receptors team up against intracellular pathogens
P Broz, DM Monack
Nature Reviews Immunology 13 (8), 551-565, 2013
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
P Broz, T Ruby, K Belhocine, DM Bouley, N Kayagaki, VM Dixit, ...
Nature 490 (7419), 288-291, 2012
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
L Sborgi, S Rühl, E Mulvihill, J Pipercevic, R Heilig, H Stahlberg, ...
The EMBO journal 35 (16), 1766-1778, 2016
The V-antigen of Yersinia forms a distinct structure at the tip of injectisome needles
CA Mueller, P Broz, SA Müller, P Ringler, F Erne-Brand, I Sorg, M Kuhn, ...
Science 310 (5748), 674-676, 2005
The needle length of bacterial injectisomes is determined by a molecular ruler
L Journet, C Agrain, P Broz, GR Cornelis
Science 302 (5651), 1757-1760, 2003
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases
E Meunier, MS Dick, RF Dreier, N Schürmann, DK Broz, S Warming, ...
Nature 509 (7500), 366-370, 2014
The type III secretion system tip complex and translocon
CA Mueller, P Broz, GR Cornelis
Molecular microbiology 68 (5), 1085-1095, 2008
Molecular mechanisms of inflammasome activation during microbial infections
P Broz, DM Monack
Immunological reviews 243 (1), 174-190, 2011
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida
E Meunier, P Wallet, RF Dreier, S Costanzo, L Anton, S Rühl, ...
Nature immunology 16 (5), 476-484, 2015
Caspase‐11 activates a canonical NLRP3 inflammasome by promoting K+ efflux
S Rühl, P Broz
European journal of immunology 45 (10), 2927-2936, 2015
Innate immune response to Salmonella typhimurium, a model enteric pathogen
P Broz, MB Ohlson, DM Monack
Gut microbes 3 (2), 62-70, 2012
K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria
CJ Groß, R Mishra, KS Schneider, G Médard, J Wettmarshausen, ...
Immunity 45 (4), 761-773, 2016
ASC filament formation serves as a signal amplification mechanism for inflammasomes
MS Dick, L Sborgi, S Rühl, S Hiller, P Broz
Nature communications 7 (1), 1-13, 2016
Function and molecular architecture of the Yersinia injectisome tip complex
P Broz, CA Mueller, SA Müller, A Philippsen, I Sorg, A Engel, GR Cornelis
Molecular microbiology 65 (5), 1311-1320, 2007
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
S Rühl, K Shkarina, B Demarco, R Heilig, JC Santos, P Broz
Science 362 (6417), 956-960, 2018
Protective Anti-V Antibodies Inhibit Pseudomonas and Yersinia Translocon Assembly within Host Membranes
J Goure, P Broz, O Attree, GR Cornelis, I Attree
The Journal of infectious diseases 192 (2), 218-225, 2005
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