|Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.|
R Coulombe, P Grochulski, J Sivaraman, R Menard, JS Mort, M Cygler
The EMBO journal 15 (20), 5492-5503, 1996
|Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion|
M Cygler, J Sivaraman, P Grochulski, R Coulombe, AC Storer, JS Mort
Structure 4 (4), 405-416, 1996
|Inhibition of bacterial cell division protein FtsZ by cinnamaldehyde|
P Domadia, S Swarup, A Bhunia, J Sivaraman, D Dasgupta
Biochemical pharmacology 74 (6), 831-840, 2007
|Linkers in the structural biology of protein–protein interactions|
VP Reddy Chichili, V Kumar, J Sivaraman
Protein Science 22 (2), 153-167, 2013
|Berberine targets assembly of Escherichia coli cell division protein FtsZ|
PN Domadia, A Bhunia, J Sivaraman, S Swarup, D Dasgupta
Biochemistry 47 (10), 3225-3234, 2008
|Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism|
K Thangavelu, CQ Pan, T Karlberg, G Balaji, M Uttamchandani, V Suresh, ...
Proceedings of the National Academy of Sciences 109 (20), 7705-7710, 2012
|Structural basis for the inhibition mechanism of human cystathionine γ-lyase, an enzyme responsible for the production of H2S|
Q Sun, R Collins, S Huang, L Holmberg-Schiavone, GS Anand, CH Tan, ...
Journal of Biological Chemistry 284 (5), 3076-3085, 2009
|Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus–host interaction|
S Li, X Tang, J Seetharaman, C Yang, Y Gu, J Zhang, H Du, JWK Shih, ...
PLoS Pathog 5 (8), e1000537, 2009
|Structural basis for the neutralization and genotype specificity of hepatitis E virus|
X Tang, C Yang, Y Gu, C Song, X Zhang, Y Wang, J Zhang, CL Hew, S Li, ...
Proceedings of the National Academy of Sciences 108 (25), 10266-10271, 2011
|Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine|
J Sivaraman, DK Nägler, R Zhang, R Ménard, M Cygler
Journal of molecular biology 295 (4), 939-951, 2000
|Two-component PhoB-PhoR regulatory system and ferric uptake regulator sense phosphate and iron to control virulence genes in type III and VI secretion systems of Edwardsiella tarda|
S Chakraborty, J Sivaraman, KY Leung, YK Mok
Journal of Biological Chemistry 286 (45), 39417-39430, 2011
|Crystal structures of major envelope proteins VP26 and VP28 from white spot syndrome virus shed light on their evolutionary relationship|
X Tang, J Wu, J Sivaraman, CL Hew
Journal of virology 81 (12), 6709-6717, 2007
|Three-Dimensional Structure of 2-Amino-3-ketobutyrate CoA Ligase from Escherichia coli Complexed with a PLP−Substrate Intermediate: Inferred Reaction …|
A Schmidt, J Sivaraman, Y Li, R Larocque, JARG Barbosa, C Smith, ...
Biochemistry 40 (17), 5151-5160, 2001
|Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides|
SF Chowdhury, J Sivaraman, J Wang, G Devanathan, P Lachance, H Qi, ...
Journal of medicinal chemistry 45 (24), 5321-5329, 2002
|Structure and evolutionary origin of Ca 2+-dependent herring type II antifreeze protein|
Y Liu, Z Li, Q Lin, J Kosinski, J Seetharaman, JM Bujnicki, J Sivaraman, ...
PLoS One 2 (6), e548, 2007
|Structural and functional characterization of a novel homodimeric three-finger neurotoxin from the venom of Ophiophagus hannah (king cobra)|
A Roy, X Zhou, MZ Chong, D D'hoedt, CS Foo, N Rajagopalan, ...
Journal of Biological Chemistry 285 (11), 8302-8315, 2010
|Specificity Determinants of Human Cathepsin S Revealed by Crystal Structures of Complexes,|
TA Pauly, T Sulea, M Ammirati, J Sivaraman, DE Danley, MC Griffor, ...
Biochemistry 42 (11), 3203-3213, 2003
|Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP|
J Sivaraman, V Sauvé, R Larocque, EA Stura, JD Schrag, M Cygler, ...
nature structural biology 9 (5), 353-358, 2002
|The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide|
O Quraishi, DK Nägler, T Fox, J Sivaraman, M Cygler, JS Mort, AC Storer
Biochemistry 38 (16), 5017-5023, 1999
|Crystal structure of Escherichia coli glucose-1-phosphate thymidylyltransferase (RffH) complexed with dTTP and Mg2+|
J Sivaraman, V Sauvé, A Matte, M Cygler
Journal of Biological Chemistry 277 (46), 44214-44219, 2002