David Dougan
David Dougan
La Trobe University, La Trobe Institute for Molecular Science
Verified email at latrobe.edu.au - Homepage
Cited by
Cited by
Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB
J Weibezahn, P Tessarz, C Schlieker, R Zahn, Z Maglica, S Lee, ...
Cell 119 (5), 653-665, 2004
ClpS, a substrate modulator of the ClpAP machine
DA Dougan, BG Reid, AL Horwich, B Bukau
Molecular cell 9 (3), 673-683, 2002
AAA+ proteins and substrate recognition, it all depends on their partner in crime
DA Dougan, A Mogk, K Zeth, K Turgay, B Bukau
FEBS letters 529 (1), 6-10, 2002
ClpS is an essential component of the N-end rule pathway in Escherichia coli
A Erbse, R Schmidt, T Bornemann, J Schneider-Mergener, A Mogk, ...
Nature 439 (7077), 753-756, 2006
Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases
J Kirstein, N Molière, DA Dougan, K Turgay
Nature Reviews Microbiology 7 (8), 589-599, 2009
Protein folding and degradation in bacteria:¶ To degrade or not to degrade? That is the question
DA Dougan, A Mogk, B Bukau
Cellular and Molecular Life Sciences CMLS 59 (10), 1607-1616, 2002
MecA, an adaptor protein necessary for ClpC chaperone activity
T Schlothauer, A Mogk, DA Dougan, B Bukau, K Turgay
Proceedings of the National Academy of Sciences 100 (5), 2306-2311, 2003
Adaptor protein controlled oligomerization activates the AAA+ protein ClpC
J Kirstein, T Schlothauer, DA Dougan, H Lilie, G Tischendorf, A Mogk, ...
The EMBO journal 25 (7), 1481-1491, 2006
Structural analysis of the adaptor protein ClpS in complex with the N-terminal domain of ClpA
K Zeth, RB Ravelli, K Paal, S Cusack, B Bukau, DA Dougan
Nature structural biology 9 (12), 906-911, 2002
Targeted delivery of an ssrA-tagged substrate by the adaptor protein SspB to its cognate AAA+ protein ClpX
DA Dougan, E Weber-Ban, B Bukau
Molecular cell 12 (2), 373-380, 2003
Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane
AJ Johnston, J Hoogenraad, DA Dougan, KN Truscott, M Yano, M Mori, ...
Journal of Biological Chemistry 277 (44), 42197-42204, 2002
The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+ proteases
DA Dougan, D Micevski, KN Truscott
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (1), 83-91, 2012
Effects of substitutions in the binding surface of an antibody on antigen affinity.
DA Dougan, RL Malby, LC Gruen, AA Kortt, PJ Hudson
Protein engineering 11 (1), 65-74, 1998
Modification of PATase by L/F‐transferase generates a ClpS‐dependent N‐end rule substrate in Escherichia coli
RL Ninnis, SK Spall, GH Talbo, KN Truscott, DA Dougan
The EMBO journal 28 (12), 1732-1744, 2009
The bacterial N‐end rule pathway: expect the unexpected
DA Dougan, KN Truscott, K Zeth
Molecular microbiology 76 (3), 545-558, 2010
Structural basis of N‐end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS
VJ Schuenemann, SM Kralik, R Albrecht, SK Spall, KN Truscott, ...
EMBO reports 10 (5), 508-514, 2009
The tyrosine kinase McsB is a regulated adaptor protein for ClpCP
J Kirstein, DA Dougan, U Gerth, M Hecker, K Turgay
The EMBO Journal 26 (8), 2061-2070, 2007
LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins
A Bezawork-Geleta, EJ Brodie, DA Dougan, KN Truscott
Scientific reports 5 (1), 1-13, 2015
Broad yet high substrate specificity: the challenge of AAA+ proteins
A Mogk, D Dougan, J Weibezahn, C Schlieker, K Turgay, B Bukau
Journal of structural biology 146 (1-2), 90-98, 2004
Machines of destruction–AAA+ proteases and the adaptors that control them
E Gur, R Ottofueling, DA Dougan
Regulated proteolysis in microorganisms, 3-33, 2013
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