Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons J Pujols, S Peña-Díaz, DF Lázaro, F Peccati, F Pinheiro, D González, ... Proceedings of the National Academy of Sciences 115 (41), 10481-10486, 2018 | 193 | 2018 |
Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals A Taglialegna, S Navarro, S Ventura, JA Garnett, S Matthews, ... PLoS pathogens 12 (6), e1005711, 2016 | 175 | 2016 |
Eosinophil cationic protein high-affinity binding to bacteria-wall lipopolysaccharides and peptidoglycans M Torrent, S Navarro, M Moussaoui, MV Nogués, E Boix Biochemistry 47 (11), 3544-3555, 2008 | 140 | 2008 |
The cytotoxicity of eosinophil cationic protein/ribonuclease 3 on eukaryotic cell lines takes place through its aggregation on the cell membrane S Navarro, J Aleu, M Jimenez, E Boix, CM Cuchillo, MV Nogues Cellular and Molecular Life Sciences 65, 324-337, 2008 | 115 | 2008 |
BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways L Jubierre, A Soriano, L Planells-Ferrer, L París-Coderch, SP Tenbaum, ... Oncogene 35 (39), 5179-5190, 2016 | 85 | 2016 |
Surface-exposed amino acids of eosinophil cationic protein play a critical role in the inhibition of mammalian cell proliferation E Carreras, E Boix, S Navarro, HF Rosenberg, CM Cuchillo, MV Nogués Molecular and cellular biochemistry 272, 1-7, 2005 | 85 | 2005 |
High-throughput screening methodology to identify alpha-synuclein aggregation inhibitors J Pujols, S Peña-Díaz, M Conde-Giménez, F Pinheiro, S Navarro, ... International journal of molecular sciences 18 (3), 478, 2017 | 77 | 2017 |
Topography studies on the membrane interaction mechanism of the eosinophil cationic protein M Torrent, E Cuyás, E Carreras, S Navarro, O López, A De La Maza, ... Biochemistry 46 (3), 720-733, 2007 | 73 | 2007 |
Dissecting the contribution of Staphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure P Marinelli, I Pallares, S Navarro, S Ventura Scientific reports 6 (1), 34552, 2016 | 68 | 2016 |
A human ribonuclease induces apoptosis associated with p21WAF1/CIP1induction and JNK inactivation J Castro, M Ribó, S Navarro, MV Nogués, M Vilanova, A Benito BMC cancer 11, 1-12, 2011 | 61 | 2011 |
Fluorescent dye ProteoStat to detect and discriminate intracellular amyloid‐like aggregates in Escherichia coli S Navarro, S Ventura Biotechnology journal 9 (10), 1259-1266, 2014 | 59 | 2014 |
The biofilm-associated surface protein Esp of Enterococcus faecalis forms amyloid-like fibers A Taglialegna, L Matilla-Cuenca, P Dorado-Morales, S Navarro, ... npj Biofilms and Microbiomes 6 (1), 15, 2020 | 53 | 2020 |
α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity J Santos, P Gracia, S Navarro, S Peña-Díaz, J Pujols, N Cremades, ... Nature communications 12 (1), 3752, 2021 | 51 | 2021 |
The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation DF Lázaro, MC Dias, A Carija, S Navarro, CS Madaleno, S Tenreiro, ... Acta neuropathologica communications 4, 1-15, 2016 | 50 | 2016 |
pH-responsive self-assembly of amyloid fibrils for dual hydrolase-oxidase reactions M Díaz-Caballero, S Navarro, M Nuez-Martínez, F Peccati, ... ACS catalysis 11 (2), 595-607, 2020 | 49 | 2020 |
Protein aggregation into insoluble deposits protects from oxidative stress A Carija, S Navarro, NS de Groot, S Ventura Redox biology 12, 699-711, 2017 | 49 | 2017 |
Combining structural aggregation propensity and stability predictions to redesign protein solubility M Gil-Garcia, M Bano-Polo, N Varejao, M Jamroz, A Kuriata, ... Molecular pharmaceutics 15 (9), 3846-3859, 2018 | 48 | 2018 |
Eosinophil-induced neurotoxicity: the role of eosinophil cationic protein/RNase 3 S Navarro, E Boix, CM Cuchillo, MV Nogués Journal of neuroimmunology 227 (1-2), 60-70, 2010 | 48 | 2010 |
Characterization of amyloid cores in prion domains R Sant’Anna, MR Fernández, C Batlle, S Navarro, NS De Groot, L Serpell, ... Scientific reports 6 (1), 34274, 2016 | 47 | 2016 |
Minimalist prion-inspired polar self-assembling peptides M Díaz-Caballero, S Navarro, I Fuentes, F Teixidor, S Ventura ACS nano 12 (6), 5394-5407, 2018 | 46 | 2018 |