Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy A Aytes, A Mitrofanova, C Lefebvre, MJ Alvarez, M Castillo-Martin, ... Cancer cell 25 (5), 638-651, 2014 | 325 | 2014 |
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing S Melo, A Villanueva, C Moutinho, V Davalos, R Spizzo, C Ivan, S Rossi, ... Proceedings of the National Academy of Sciences 108 (11), 4394-4399, 2011 | 269 | 2011 |
DNA-PKcs-mediated transcriptional regulation drives prostate cancer progression and metastasis JF Goodwin, V Kothari, JM Drake, S Zhao, E Dylgjeri, JL Dean, ... Cancer cell 28 (1), 97-113, 2015 | 177 | 2015 |
Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer V Fernandez-Majada, C Aguilera, A Villanueva, F Vilardell, ... Proceedings of the National Academy of Sciences 104 (1), 276-281, 2007 | 167 | 2007 |
A molecular signature predictive of indolent prostate cancer S Irshad, M Bansal, M Castillo-Martin, T Zheng, A Aytes, S Wenske, ... Science translational medicine 5 (202), 202ra122-202ra122, 2013 | 164 | 2013 |
ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer A Aytes, A Mitrofanova, CW Kinkade, C Lefebvre, M Lei, V Phelan, ... Proceedings of the National Academy of Sciences 110 (37), E3506-E3515, 2013 | 161 | 2013 |
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer CA Maxwell, J Benítez, L Gómez-Baldó, A Osorio, N Bonifaci, ... PLoS biology 9 (11), e1001199, 2011 | 134 | 2011 |
B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer J Wang, T Kobayashi, N Floc'h, CW Kinkade, A Aytes, D Dankort, ... Cancer research 72 (18), 4765-4776, 2012 | 107 | 2012 |
BRCA2 and other DDR genes in prostate cancer P Nombela, R Lozano, A Aytes, J Mateo, D Olmos, E Castro Cancers 11 (3), 352, 2019 | 92 | 2019 |
Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model N Floc'h, CW Kinkade, T Kobayashi, A Aytes, C Lefebvre, A Mitrofanova, ... Cancer research 72 (17), 4483-4493, 2012 | 89 | 2012 |
A modular master regulator landscape controls cancer transcriptional identity EO Paull, A Aytes, SJ Jones, PS Subramaniam, FM Giorgi, EF Douglass, ... Cell 184 (2), 334-351. e20, 2021 | 83 | 2021 |
NSD2 is a conserved driver of metastatic prostate cancer progression A Aytes, A Giacobbe, A Mitrofanova, K Ruggero, J Cyrta, J Arriaga, ... Nature communications 9 (1), 5201, 2018 | 83 | 2018 |
New perspectives on screening and early detection of endometrial cancer L Costas, J Frias‐Gomez, M Guardiola, Y Benavente, M Pineda, ... International journal of cancer 145 (12), 3194-3206, 2019 | 65 | 2019 |
Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype A Aytes, DG Molleví, M Martinez‐Iniesta, M Nadal, A Vidal, A Morales, ... Molecular carcinogenesis 51 (9), 746-753, 2012 | 65 | 2012 |
Epigenetic regulation in prostate cancer progression K Ruggero, S Farran-Matas, A Martinez-Tebar, A Aytes Current molecular biology reports 4, 101-115, 2018 | 62 | 2018 |
PRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressiveness DG Molleví, A Aytes, L Padullés, M Martínez-Iniesta, N Baixeras, ... British journal of cancer 99 (10), 1718-1725, 2008 | 53 | 2008 |
Predicting drug response in human prostate cancer from preclinical analysis of in vivo mouse models A Mitrofanova, A Aytes, M Zou, MM Shen, C Abate-Shen, A Califano Cell reports 12 (12), 2060-2071, 2015 | 45 | 2015 |
Loss of TGFβ signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types Q Liu, L Palomero, J Moore, I Guix, R Espín, A Aytés, JH Mao, ... Science translational medicine 13 (580), eabc4465, 2021 | 38 | 2021 |
Sensitivity of cervico‐vaginal cytology in endometrial carcinoma: a systematic review and meta‐analysis J Frias‐Gomez, Y Benavente, J Ponce, J Brunet, R Ibáñez, ... Cancer Cytopathology 128 (11), 792-802, 2020 | 37 | 2020 |
Chemotherapy in metastatic castration-resistant prostate cancer: current scenario and future perspectives VR de Porras, A Font, A Aytes Cancer letters 523, 162-169, 2021 | 34 | 2021 |