Jacek Jemielity
Jacek Jemielity
Centre of New Technologies, University of Warsaw
Zweryfikowany adres z biogeo.uw.edu.pl - Strona główna
Cytowane przez
Cytowane przez
Novel “anti-reverse” cap analogs with superior translational properties
J Jemielity, T Fowler, J Zuberek, J Stepinski, M Lewdorowicz, ...
Rna 9 (9), 1108-1122, 2003
Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells
E Grudzien-Nogalska, J Jemielity, J Kowalska, E Darzynkiewicz, ...
Rna 13 (10), 1745-1755, 2007
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
AN Kuhn, M Diken, S Kreiter, A Selmi, J Kowalska, J Jemielity, ...
Gene therapy 17 (8), 961-971, 2010
The strategies to support the COVID-19 vaccination with evidence-based communication and tackling misinformation
P Rzymski, L Borkowski, M Drąg, R Flisiak, J Jemielity, J Krajewski, ...
Vaccines 9 (2), 109, 2021
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS
J Kowalska, M Lewdorowicz, J Zuberek, E Grudzien-Nogalska, ...
Rna 14 (6), 1119-1131, 2008
mRNA decapping is promoted by an RNA-binding channel in Dcp2
MV Deshmukh, BN Jones, DU Quang-Dang, J Flinders, SN Floor, C Kim, ...
Molecular cell 29 (3), 324-336, 2008
Differential inhibition of mRNA degradation pathways by novel cap analogs
E Grudzien, M Kalek, J Jemielity, E Darzynkiewicz, RE Rhoads
Journal of Biological Chemistry 281 (4), 1857-1867, 2006
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression
A Zdanowicz, R Thermann, J Kowalska, J Jemielity, K Duncan, T Preiss, ...
Molecular cell 35 (6), 881-888, 2009
Synthesis of anti‐reverse cap analogs (ARCAs) and their applications in mRNA translation and stability
E Grudzien‐Nogalska, J Stepinski, J Jemielity, J Zuberek, R Stolarski, ...
Methods in enzymology 431, 203-227, 2007
Vaccine composition comprising 5′-cap modified RNA
U Sahin, A Kuhn, E Darzynkiewicz, J Jemielity, J Kowalska
US Patent 9,295,717, 2016
Weak binding affinity of human 4EHP for mRNA cap analogs
J Zuberek, D Kubacka, A Jablonowska, J Jemielity, J Stepinski, ...
Rna 13 (5), 691-697, 2007
Synthetic mRNA cap analogs with a modified triphosphate bridge–synthesis, applications and prospects
J Jemielity, J Kowalska, AM Rydzik, E Darzynkiewicz
New Journal of Chemistry 34 (5), 829-844, 2010
The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells
PJ Sikorski, M Warminski, D Kubacka, T Ratajczak, D Nowis, J Kowalska, ...
Nucleic Acids Research 48 (4), 1607-1626, 2020
Influence of Electric Charge Variation at Residues 209 and 159 on the Interaction of eIF4E with the mRNA 5 ‘Terminus
J Zuberek, J Jemielity, A Jablonowska, J Stepinski, M Dadlez, R Stolarski, ...
Biochemistry 43 (18), 5370-5379, 2004
Potential therapeutic applications of RNA cap analogs
M Ziemniak, M Strenkowska, J Kowalska, J Jemielity
Future medicinal chemistry 5 (10), 1141-1172, 2013
Cap analogs modified with 1, 2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential
M Strenkowska, R Grzela, M Majewski, K Wnek, J Kowalska, ...
Nucleic acids research 44 (20), 9578-9590, 2016
5′-phosphorothiolate dinucleotide cap analogues: Reagents for messenger RNA modification and potent small-molecular inhibitors of decapping enzymes
BA Wojtczak, PJ Sikorski, K Fac-Dabrowska, A Nowicka, M Warminski, ...
Journal of the American Chemical Society 140 (18), 5987-5999, 2018
Synthetic mRNAs with superior translation and stability properties
E Grudzien-Nogalska, J Kowalska, W Su, AN Kuhn, SV Slepenkov, ...
Synthetic Messenger RNA and Cell Metabolism Modulation: Methods and …, 2013
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes
J Kowalska, AW del Nogal, ZM Darzynkiewicz, J Buck, C Nicola, AN Kuhn, ...
Nucleic acids research 42, 10245-10264, 2014
Synthesis and use of anti-reverse phosphorothioate analogs of the messenger RNA cap
J Jemielity, EM Grudzien-Nogalska, J Kowalska, E Darzynkiewicz, ...
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