Obserwuj
Tõnis Lehto
Tõnis Lehto
Post doctoral fellow, University of Tartu
Zweryfikowany adres z ut.ee
Tytuł
Cytowane przez
Cytowane przez
Rok
PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo
KL Veiman, K Künnapuu, T Lehto, K Kiisholts, K Pärn, Ü Langel, ...
Journal of Controlled Release 209, 238-247, 2015
1322015
PepFect14 peptide vector for efficient gene delivery in cell cultures
KL Veiman, I Mäger, K Ezzat, H Margus, T Lehto, K Langel, K Kurrikoff, ...
Molecular pharmaceutics 10 (1), 199-210, 2013
1012013
Saturated fatty acid analogues of cell-penetrating peptide PepFect14: role of fatty acid modification in complexation and delivery of splice-correcting oligonucleotides
T Lehto, L Vasconcelos, H Margus, R Figueroa, M Pooga, M Hällbrink, ...
Bioconjugate chemistry 28 (3), 782-792, 2017
492017
Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide
K Kurrikoff, KL Veiman, K Künnapuu, EM Peets, T Lehto, L Pärnaste, ...
Scientific reports 7 (1), 17056, 2017
402017
Efficient peptide-mediated in vitro delivery of Cas9 RNP
O Gustafsson, J Rädler, S Roudi, T Lehto, M Hällbrink, T Lehto, D Gupta, ...
Pharmaceutics 13 (6), 878, 2021
272021
Peptide-based vectors: recent developments
CP Cerrato, T Lehto, Ü Langel
Biomolecular concepts 5 (6), 479-488, 2014
252014
Intracellular delivery of therapeutic antisense oligonucleotides targeting mRNA coding mitochondrial proteins by cell-penetrating peptides
CP Cerrato, T Kivijärvi, R Tozzi, T Lehto, M Gestin, Ü Langel
Journal of Materials Chemistry B 8 (47), 10825-10836, 2020
202020
Refinement of a quantitative structure–activity relationship model for prediction of cell-penetrating peptide based transfection systems
M Dowaidar, J Regberg, DA Dobchev, T Lehto, M Hällbrink, M Karelson, ...
International Journal of Peptide Research and Therapeutics 23, 91-100, 2017
192017
Simultaneous membrane interaction of amphipathic peptide monomers, self-aggregates and cargo complexes detected by fluorescence correlation spectroscopy
L Vasconcelos, T Lehto, F Madani, V Radoi, M Hällbrink, V Vukojević, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (2), 491-504, 2018
162018
Astrocytes promote ethanol-induced enhancement of intracellular Ca2+ signals through intercellular communication with neurons
HB Kim, J Morris, K Miyashiro, T Lehto, Ü Langel, J Eberwine, JY Sul
Iscience 24 (5), 2021
92021
Novel orthogonally hydrocarbon-modified cell-penetrating peptide nanoparticles mediate efficient delivery of splice-switching antisense oligonucleotides in vitro and in vivo
S Bazaz, T Lehto, R Tops, O Gissberg, D Gupta, B Bestas, J Bost, ...
Biomedicines 9 (8), 1046, 2021
62021
Characterization of nucleic acid delivery with fatty acid modified cell-penetrating peptide nanoparticle formulations
T Lehto
Department of Biochemistry and Biophysics, Stockholm University, 2018
12018
Guidelines for developing safe and efficient acylated cell-penetrating peptides for nanoparticle mediated non-covalent nucleic acid delivery in vivo
T Lehto
2018
Principles of in vivo nucleic acid delivery with acylated cell-penetrating peptides
T Lehto, KL Veiman, M Hällbrink, Ü Langel
Nie można teraz wykonać tej operacji. Spróbuj ponownie później.
Prace 1–14