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Eachan Johnson
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Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes
EO Johnson, E LaVerriere, E Office, M Stanley, E Meyer, T Kawate, ...
Nature 571 (7763), 72-78, 2019
852019
Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation
J Boehringer, C Riedinger, K Paraskevopoulos, EOD Johnson, ED Lowe, ...
Biochemical Journal 448 (1), 55-65, 2012
732012
Selective oxidative demethylation of veratric acid to vanillic acid by CYP199A4 from Rhodopseudomonas palustris HaA2
SG Bell, ABH Tan, EOD Johnson, LL Wong
Molecular BioSystems 6 (1), 206-214, 2009
602009
Protein recognition in ferredoxin–P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris
SG Bell, F Xu, EOD Johnson, IM Forward, M Bartlam, Z Rao, LL Wong
JBIC Journal of Biological Inorganic Chemistry 15 (3), 315-328, 2010
572010
Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris
F Xu, SG Bell, Y Peng, EOD Johnson, M Bartlam, Z Rao, LL Wong
Proteins: Structure, Function, and Bioinformatics 77 (4), 867-880, 2009
422009
The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site
SG Bell, W Yang, ABH Tan, R Zhou, EOD Johnson, A Zhang, W Zhou, ...
Dalton Transactions 41 (28), 8703-8714, 2012
382012
Tailoring an alien ferredoxin to support native-like P450 monooxygenase activity
SG Bell, JHC McMillan, JA Yorke, E Kavanagh, EOD Johnson, LL Wong
Chemical Communications 48 (95), 11692-11694, 2012
302012
A structural model of a P450-ferredoxin complex from orientation-selective double electron–electron resonance spectroscopy
AM Bowen, EOD Johnson, F Mercuri, NJ Hoskins, R Qiao, ...
Journal of the American Chemical Society 140 (7), 2514-2527, 2018
172018
Partial fusion of a cytochrome P450 system by carboxy-terminal attachment of putidaredoxin reductase to P450cam (CYP101A1)
EOD Johnson, LL Wong
Catalysis science & technology 6 (20), 7549-7560, 2016
82016
Large-Scale Chemical-Genetic Strategy Enables the Design of Antimicrobial Combination Chemotherapy in Mycobacteria
EO Johnson, E Office, T Kawate, M Orzechowski, DT Hung
ACS infectious diseases, 2019
72019
A point of inflection and reflection on systems chemical biology
EO Johnson, DT Hung
ACS Chemical Biology 14 (12), 2497-2511, 2019
72019
Office E., Kawate T., Orzechowski M., Hung DT (2020)
EO Johnson
Large-scale chemical-genetic strategy enables the design of antimicrobial …, 0
5
Using proteolytic hypomorphs to detect small molecule mechanism of action
EO Johnson, DT Hung
Mycobacteria Protocols, 323-342, 2021
12021
Multiplex high-resolution detection of micro-organism strains, related kits, diagnostics methods and screening assays
D Hung, E Johnson, B Poulsen
US Patent App. WO2017079699A1, 2017
12017
Protein-protein recognition in biological systems exhibiting highly-conserved tertiary structure: cytochrome P450
EOD Johnson
University of Oxford, 2013
2013
Evolution Mycobacterium tuberculosis drug resistance in the genomic era
C Nimmo, J Millard, V Faulkner, J Monteserin, H Pugh, S Parkhill, ...
Frontiers in Cellular and Infection Microbiology, 1502, 0
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