| Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α CA Thorne, AJ Hanson, J Schneider, E Tahinci, D Orton, CS Cselenyi, ... Nature chemical biology 6 (11), 829-836, 2010 | 515 | 2010 |
| The way Wnt works: components and mechanism K Saito-Diaz, TW Chen, X Wang, CA Thorne, HA Wallace, A Page-McCaw, ... Growth factors 31 (1), 1-31, 2013 | 282 | 2013 |
| LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of β-catenin CS Cselenyi, KK Jernigan, E Tahinci, CA Thorne, LA Lee, E Lee Proceedings of the National Academy of Sciences 105 (23), 8032-8037, 2008 | 257 | 2008 |
| Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling S Saraswati, MP Alfaro, CA Thorne, J Atkinson, E Lee, PP Young PloS one 5 (11), e15521, 2010 | 228 | 2010 |
| Enteroid monolayers reveal an autonomous WNT and BMP circuit controlling intestinal epithelial growth and organization CA Thorne, IW Chen, LE Sanman, MH Cobb, LF Wu, SJ Altschuler Developmental cell 44 (5), 624-633. e4, 2018 | 155 | 2018 |
| sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair MP Alfaro, A Vincent, S Saraswati, CA Thorne, CC Hong, E Lee, ... Journal of Biological Chemistry 285 (46), 35645-35653, 2010 | 153 | 2010 |
| FGF21 is an exocrine pancreas secretagogue KC Coate, G Hernandez, CA Thorne, S Sun, TDV Le, K Vale, SA Kliewer, ... Cell metabolism 25 (2), 472-480, 2017 | 120 | 2017 |
| Pyrvinium for the Treatment of Cancer E Lee, L Lee, C Thorne, E Tahinci, KC Meyers US Patent App. 12/129,250, 2009 | 96 | 2009 |
| Lrp6 is required for convergent extension during Xenopusgastrulation E Tahinci, CA Thorne, JL Franklin, A Salic, KM Christian, LA Lee, ... Oxford University Press for The Company of Biologists Limited 134 (22), 4095 …, 2007 | 87 | 2007 |
| Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen J Hao, A Ao, L Zhou, CK Murphy, AY Frist, JJ Keel, CA Thorne, K Kim, ... Cell reports 4 (5), 898-904, 2013 | 73 | 2013 |
| Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals EC Chen, P Gilchuk, SJ Zost, N Suryadevara, ES Winkler, CR Cabel, ... Cell Reports 36 (8), 2021 | 71 | 2021 |
| Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling TT Ni, EJ Rellinger, A Mukherjee, S Xie, L Stephens, CA Thorne, K Kim, ... Chemistry & biology 18 (12), 1658-1668, 2011 | 69 | 2011 |
| Gβγ activates GSK3 to promote LRP6-mediated β-catenin transcriptional activity KK Jernigan, CS Cselenyi, CA Thorne, AJ Hanson, E Tahinci, N Hajicek, ... Science signaling 3 (121), ra37-ra37, 2010 | 62* | 2010 |
| Cross talk between estrogen receptor and IGF signaling in normal mammary gland development and breast cancer C Thorne, AV Lee Breast disease 17 (1), 105-114, 2003 | 44 | 2003 |
| GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors CA Thorne, C Wichaidit, AD Coster, BA Posner, LF Wu, SJ Altschuler Nature chemical biology 11 (1), 58-63, 2015 | 42 | 2015 |
| Novel compounds targeting neuropilin receptor 1 with potential to interfere with SARS-CoV-2 virus entry S Perez-Miller, M Patek, A Moutal, P Duran, CR Cabel, CA Thorne, ... ACS chemical neuroscience 12 (8), 1299-1312, 2021 | 36 | 2021 |
| Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors B Li, D Orton, LR Neitzel, L Astudillo, C Shen, J Long, X Chen, ... Science signaling 10 (485), eaak9916, 2017 | 33 | 2017 |
| Wnt/Wingless pathway activation is promoted by a critical threshold of Axin maintained by the tumor suppressor APC and the ADP-ribose polymerase Tankyrase Z Wang, O Tacchelly-Benites, E Yang, CA Thorne, H Nojima, E Lee, ... Genetics 203 (1), 269-281, 2016 | 33 | 2016 |
| Wnt/β-catenin signaling in tissue self-organization KW Pond, K Doubrovinski, CA Thorne Genes 11 (8), 939, 2020 | 26 | 2020 |
| Paradoxical effects of cigarette smoke and COPD on SARS-CoV-2 infection and disease M Tomchaney, M Contoli, J Mayo, S Baraldo, S Li, CR Cabel, DA Bull, ... BMC Pulmonary Medicine 21, 1-14, 2021 | 20 | 2021 |
