TLR4 mutations are associated with endotoxin hyporesponsiveness in humans NC Arbour, E Lorenz, BC Schutte, J Zabner, JN Kline, M Jones, K Frees, ... Nature genetics 25 (2), 187-191, 2000 | 2567 | 2000 |
Immunostimulatory nucleic acid molecules AM Krieg, J Kline, D Klinman, AD Steinberg US Patent 6,207,646, 2001 | 775* | 2001 |
Cutting edge: modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma JN Kline, TJ Waldschmidt, TR Businga, JE Lemish, JV Weinstock, ... The Journal of Immunology 160 (6), 2555-2559, 1998 | 750 | 1998 |
Motile cilia of human airway epithelia are chemosensory AS Shah, Y Ben-Shahar, TO Moninger, JN Kline, MJ Welsh Science 325 (5944), 1131-1134, 2009 | 726 | 2009 |
Immunostimulatory nucleic acid molecules AM Krieg, JN Kline US Patent 6,239,116, 2001 | 662 | 2001 |
Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis TB Casale, WW Busse, JN Kline, ZK Ballas, MH Moss, RG Townley, ... Journal of Allergy and Clinical Immunology 117 (1), 134-140, 2006 | 396 | 2006 |
Bronchial thermoplasty: long-term safety and effectiveness in patients with severe persistent asthma ME Wechsler, M Laviolette, AS Rubin, J Fiterman, JRL e Silva, PL Shah, ... Journal of allergy and clinical immunology 132 (6), 1295-1302. e3, 2013 | 367 | 2013 |
Variable airway responsiveness to inhaled lipopolysaccharide JN Kline, JD Cowden, GW HUNNINGHAKE, BC Schutte, JL Watt, ... American journal of respiratory and critical care medicine 160 (1), 297-303, 1999 | 270 | 1999 |
Health effects of airborne exposures from concentrated animal feeding operations D Heederik, T Sigsgaard, PS Thorne, JN Kline, R Avery, JH Bønløkke, ... Environmental health perspectives 115 (2), 298-302, 2007 | 269 | 2007 |
Asthma guidelines: an assessment of physician understanding and practice KC Doerschug, MW Peterson, CS Dayton, JN Kline American journal of respiratory and critical care medicine 159 (6), 1735-1741, 1999 | 253 | 1999 |
Intestinal helminths protect in a murine model of asthma K Kitagaki, TR Businga, D Racila, DE Elliott, JV Weinstock, JN Kline The Journal of Immunology 177 (3), 1628-1635, 2006 | 251 | 2006 |
Phase I/II randomized trial of aerobic exercise in Parkinson disease in a community setting EY Uc, KC Doerschug, V Magnotta, JD Dawson, TR Thomsen, JN Kline, ... Neurology 83 (5), 413-425, 2014 | 244 | 2014 |
Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial WW Busse, ER Bleecker, JM FitzGerald, GT Ferguson, P Barker, ... The lancet respiratory medicine 7 (1), 46-59, 2019 | 239 | 2019 |
Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2 HP Jia, JN Kline, A Penisten, MA Apicella, TL Gioannini, J Weiss, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 287 (2 …, 2004 | 199 | 2004 |
CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma JN Kline, AM Krieg, TJ Waldschmidt, ZK Ballas, V Jain, TR Businga Journal of allergy and clinical immunology 104 (6), 1258-1264, 1999 | 185 | 1999 |
CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma VV Jain, K Kitagaki, T Businga, I Hussain, C George, P O'shaughnessy, ... Journal of Allergy and Clinical Immunology 110 (6), 867-872, 2002 | 184 | 2002 |
Treatment of established asthma in a murine model using CpG oligodeoxynucleotides JN Kline, K Kitagaki, TR Businga, VV Jain American Journal of Physiology-Lung Cellular and Molecular Physiology 283 (1 …, 2002 | 184 | 2002 |
Use of CpG oligonucleotides in treatment of asthma and allergic disease DE Fonseca, JN Kline Advanced drug delivery reviews 61 (3), 256-262, 2009 | 168 | 2009 |
MMP9 modulates tight junction integrity and cell viability in human airway epithelia PD Vermeer, J Denker, M Estin, TO Moninger, S Keshavjee, P Karp, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (5 …, 2009 | 161 | 2009 |
Placebo response in asthma: a robust and objective phenomenon ME Kemeny, LJ Rosenwasser, RA Panettieri, RM Rose, SM Berg-Smith, ... Journal of Allergy and Clinical Immunology 119 (6), 1375-1381, 2007 | 152 | 2007 |