Janine Kirstein
Janine Kirstein
Verified email at uni-bremen.de - Homepage
Cited by
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Metazoan Hsp70 machines use Hsp110 to power protein disaggregation
H Rampelt, J Kirstein‐Miles, NB Nillegoda, K Chi, SR Scholz, RI Morimoto, ...
The EMBO journal 31 (21), 4221-4235, 2012
Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases
J Kirstein, N Molière, DA Dougan, K Turgay
Nature Reviews Microbiology 7 (8), 589-599, 2009
Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation
NB Nillegoda, J Kirstein, A Szlachcic, M Berynskyy, A Stank, F Stengel, ...
Nature 524 (7564), 247-251, 2015
The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease
J Kirstein, A Hoffmann, H Lilie, R Schmidt, H Rübsamen‐Waigmann, ...
EMBO molecular medicine 1 (1), 37-49, 2009
Adaptor protein controlled oligomerization activates the AAA+ protein ClpC
J Kirstein, T Schlothauer, DA Dougan, H Lilie, G Tischendorf, A Mogk, ...
The EMBO journal 25 (7), 1481-1491, 2006
Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments
T Haslberger, A Zdanowicz, I Brand, J Kirstein, K Turgay, A Mogk, ...
Nature structural & molecular biology 15 (6), 641, 2008
The nascent polypeptide‐associated complex is a key regulator of proteostasis
J Kirstein‐Miles, A Scior, E Deuerling, RI Morimoto
The EMBO journal 32 (10), 1451-1468, 2013
A tyrosine kinase and its activator control the activity of the CtsR heat shock repressor in B. subtilis
J Kirstein, D Zühlke, U Gerth, K Turgay, M Hecker
The EMBO journal 24 (19), 3435-3445, 2005
In-depth profiling of the LiaR response of Bacillus subtilis
D Wolf, F Kalamorz, T Wecke, A Juszczak, U Mäder, G Homuth, S Jordan, ...
Journal of bacteriology 192 (18), 4680-4693, 2010
The tyrosine kinase McsB is a regulated adaptor protein for ClpCP
J Kirstein, DA Dougan, U Gerth, M Hecker, K Turgay
The EMBO Journal 26 (8), 2061-2070, 2007
Fine-tuning in regulation of Clp protein content in Bacillus subtilis
U Gerth, J Kirstein, J Mostertz, T Waldminghaus, M Miethke, H Kock, ...
Journal of Bacteriology 186 (1), 179-191, 2004
Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments
J Kirstein, D Morito, T Kakihana, M Sugihara, A Minnen, MS Hipp, ...
The EMBO journal 34 (18), 2334-2349, 2015
Localization of general and regulatory proteolysis in Bacillus subtilis cells
J Kirstein, H Strahl, N Molière, LW Hamoen, K Turgay
Molecular microbiology 70 (3), 682-694, 2008
Cyanobacterial ClpC/HSP100 protein displays intrinsic chaperone activity
FI Andersson, R Blakytny, J Kirstein, K Turgay, B Bukau, A Mogk, ...
Journal of Biological Chemistry 281 (9), 5468-5475, 2006
Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex
A Scior, A Buntru, K Arnsburg, A Ast, M Iburg, K Juenemann, ML Pigazzini, ...
The EMBO journal 37 (2), 282-299, 2018
A new tyrosine phosphorylation mechanism involved in signal transduction in Bacillus subtilis
J Kirstein, K Turgay
Journal of molecular microbiology and biotechnology 9 (3-4), 182-188, 2005
Substrate recognition and processing by a Walker B mutant of the human mitochondrial AAA+ protein CLPX
BR Lowth, J Kirstein-Miles, T Saiyed, H Brötz-Oesterhelt, RI Morimoto, ...
Journal of structural biology 179 (2), 193-201, 2012
Caenorhabditis elegans as a model system to study intercompartmental proteostasis: Interrelation of mitochondrial function, longevity, and neurodegenerative …
J Kirstein‐Miles, RI Morimoto
Developmental dynamics: an official publication of the American Association …, 2010
Function, evolution, and structure of J-domain proteins
HH Kampinga, C Andreasson, A Barducci, ME Cheetham, D Cyr, ...
Cell Stress and Chaperones 24 (1), 7-15, 2019
Reduced insulin/IGF-1 signaling restores the dynamic properties of key stress granule proteins during aging
MC Lechler, ED Crawford, N Groh, K Widmaier, R Jung, J Kirstein, ...
Cell reports 18 (2), 454-467, 2017
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