The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and-7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1β activation JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ... Cell reports 25 (9), 2339-2353. e4, 2018 | 187 | 2018 |
Studies toward the pharmacophore of salvinorin A, a potent κ opioid receptor agonist TA Munro, MA Rizzacasa, BL Roth, BA Toth, F Yan Journal of medicinal chemistry 48 (2), 345-348, 2005 | 150 | 2005 |
Salvinorins D−F, New Neoclerodane Diterpenoids from Salvia divinorum, and an Improved Method for the Isolation of Salvinorin A TA Munro, MA Rizzacasa Journal of natural products 66 (5), 703-705, 2003 | 115 | 2003 |
Divinatorins A−C, New Neoclerodane Diterpenoids from the Controlled Sage Salvia divinorum AK Bigham, TA Munro, MA Rizzacasa, RM Robins-Browne Journal of natural products 66 (9), 1242-1244, 2003 | 101 | 2003 |
Total synthesis of the potent anticancer Aglaia metabolites (−)-silvestrol and (−)-episilvestrol and the active analogue (−)-4′-desmethoxyepisilvestrol TE Adams, M El Sous, BC Hawkins, S Hirner, G Holloway, ML Khoo, ... Journal of the American Chemical Society 131 (4), 1607-1616, 2009 | 88 | 2009 |
Total synthesis of the epidermal growth factor inhibitor (−)-reveromycin B AN Cuzzupe, CA Hutton, MJ Lilly, RK Mann, KJ McRae, SC Zammit, ... The Journal of Organic Chemistry 66 (7), 2382-2393, 2001 | 85 | 2001 |
Formal Total Synthesis of (−)-Apicularen A via Transannular Conjugate Addition F Hilli, JM White, MA Rizzacasa Organic Letters 6 (8), 1289-1292, 2004 | 83 | 2004 |
Total synthesis of (+)-crocacin D JT Feutrill, MJ Lilly, MA Rizzacasa Organic letters 4 (4), 525-527, 2002 | 81 | 2002 |
Formal total synthesis of salicylihalamides A and B GA Holloway, HM Hügel, MA Rizzacasa The Journal of organic chemistry 68 (6), 2200-2204, 2003 | 78 | 2003 |
Total Synthesis of (−)‐Episilvestrol and (−)‐Silvestrol M El Sous, ML Khoo, G Holloway, D Owen, PJ Scammells, MA Rizzacasa Angewandte Chemie 119 (41), 7981-7984, 2007 | 76 | 2007 |
Synthesis of biotinylated episilvestrol: highly selective targeting of the translation factors eIF4AI/II JM Chambers, LM Lindqvist, A Webb, DCS Huang, GP Savage, ... Organic letters 15 (6), 1406-1409, 2013 | 70 | 2013 |
Convergent synthesis of polyether ionophore antibiotics: synthesis of the spiroketal and tricyclic glycal segments of monensin RE Ireland, JD Armstrong III, J Lebreton, RS Meissner, MA Rizzacasa Journal of the American Chemical Society 115 (16), 7152-7165, 1993 | 64 | 1993 |
Enantiospecific Synthesis of the Phospholipase A2 Inhibitor (−)-Cinatrin B AN Cuzzupe, R Di Florio, MA Rizzacasa The Journal of Organic Chemistry 67 (13), 4392-4398, 2002 | 62 | 2002 |
Mulberry Diels− Alder adducts: synthesis of chalcomoracin and mulberrofuran C methyl ethers C Gunawan, MA Rizzacasa Organic Letters 12 (7), 1388-1391, 2010 | 54 | 2010 |
The hetero-Diels–Alder approach to spiroketals MA Rizzacasa, A Pollex Organic & Biomolecular Chemistry 7 (6), 1053-1059, 2009 | 54 | 2009 |
Synthetic studies on the salicylihalamides: macrolactone formation via ring closing metathesis versus macrolactonization JT Feutrill, GA Holloway, F Hilli, HM Hügel, MA Rizzacasa Tetrahedron Letters 41 (44), 8569-8572, 2000 | 54 | 2000 |
Synthesis of the core of apicularen A by transannular conjugate addition F Hilli, JM White, MA Rizzacasa Tetrahedron letters 43 (47), 8507-8510, 2002 | 51 | 2002 |
Convergent Synthesis of Naphthylisoquinoline Alkaloids: Total Synthesis of (+)-O-Methylancistrocline P Chau, IR Czuba, MA Rizzacasa, G Bringmann, KP Gulden, M Schäffer The Journal of Organic Chemistry 61 (20), 7101-7105, 1996 | 50 | 1996 |
The synthesis of stypandrol, a toxic binaphthalenetetrol isolated from Stypandra imbricata: new syntheses of dianellidin and stypandrone MA Rizzacasa, MV Sargent Australian Journal of Chemistry 41 (7), 1087-1097, 1988 | 50 | 1988 |
Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor LM Lindqvist, I Vikström, JM Chambers, K McArthur, M Ann Anderson, ... Cell death & disease 3 (10), e409-e409, 2012 | 49 | 2012 |