Christopher Brooke
Christopher Brooke
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Most influenza a virions fail to express at least one essential viral protein
CB Brooke, WL Ince, J Wrammert, R Ahmed, PC Wilson, JR Bennink, ...
Journal of virology 87 (6), 3155-3162, 2013
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ...
Science 373 (6557), 931-936, 2021
Longitudinal assessment of diagnostic test performance over the course of acute SARS-CoV-2 infection
RL Smith, LL Gibson, PP Martinez, R Ke, A Mirza, M Conte, N Gallagher, ...
The Journal of infectious diseases 224 (6), 976-982, 2021
Defining influenza A virus hemagglutinin antigenic drift by sequential monoclonal antibody selection
SR Das, SE Hensley, WL Ince, CB Brooke, A Subba, MG Delboy, G Russ, ...
Cell host & microbe 13 (3), 314-323, 2013
Saliva-based molecular testing for SARS-CoV-2 that bypasses RNA extraction
DRE Ranoa, RL Holland, FG Alnaji, KJ Green, L Wang, CB Brooke, ...
biorxiv, 2020.06. 18.159434, 2020
Viral infection triggers rapid differentiation of human blood monocytes into dendritic cells
W Hou, JS Gibbs, X Lu, CB Brooke, D Roy, RL Modlin, JR Bennink, ...
Blood, The Journal of the American Society of Hematology 119 (13), 3128-3131, 2012
Biological activities of'noninfectious' influenza A virus particles
CB Brooke
Future virology 9 (1), 41-51, 2014
Population diversity and collective interactions during influenza virus infection
CB Brooke
Journal of Virology 91 (22), e01164-17, 2017
Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs
I Kosik, WL Ince, LE Gentles, AJ Oler, M Kosikova, M Angel, JG Magadán, ...
PLoS pathogens 14 (1), e1006796, 2018
Influenza A virus nucleoprotein selectively decreases neuraminidase gene-segment packaging while enhancing viral fitness and transmissibility
CB Brooke, WL Ince, J Wei, JR Bennink, JW Yewdell
Proceedings of the National Academy of Sciences 111 (47), 16854-16859, 2014
Longitudinal analysis of SARS-CoV-2 vaccine breakthrough infections reveals limited infectious virus shedding and restricted tissue distribution
R Ke, PP Martinez, RL Smith, LL Gibson, CJ Achenbach, S McFall, C Qi, ...
Open forum infectious diseases 9 (7), ofac192, 2022
Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness
R Ke, PP Martinez, RL Smith, LL Gibson, A Mirza, M Conte, N Gallagher, ...
Nature Microbiology 7 (5), 640-652, 2022
Neuraminidase inhibition contributes to influenza A virus neutralization by anti-hemagglutinin stem antibodies
I Kosik, D Angeletti, JS Gibbs, M Angel, K Takeda, M Kosikova, V Nair, ...
Journal of Experimental Medicine 216 (2), 304-316, 2019
Causes and consequences of spatial within-host viral spread
ME Gallagher, CB Brooke, R Ke, K Koelle
Viruses 10 (11), 627, 2018
The role of the blood-brain barrier during Venezuelan equine encephalitis virus infection
A Schafer, CB Brooke, AC Whitmore, RE Johnston
Journal of virology 85 (20), 2011
T cells facilitate recovery from Venezuelan equine encephalitis virus-induced encephalomyelitis in the absence of antibody
CB Brooke, DJ Deming, AC Whitmore, LJ White, RE Johnston
Journal of virology 84 (9), 4556-4568, 2010
Sequencing framework for the sensitive detection and precise mapping of defective interfering particle-associated deletions across influenza A and B viruses
FG Alnaji, JR Holmes, G Rendon, JC Vera, CJ Fields, BE Martin, ...
Journal of virology 93 (11), e00354-19, 2019
Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro
N Drayman, KA Jones, SA Azizi, HM Froggatt, K Tan, NI Maltseva, S Chen, ...
BioRxiv, 2020.08. 31.274639, 2020
Single cell heterogeneity in influenza A virus gene expression shapes the innate antiviral response to infection
J Sun, JC Vera, J Drnevich, YT Lin, R Ke, CB Brooke
PLoS pathogens 16 (7), e1008671, 2020
Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
TJC Tan, M Yuan, K Kuzelka, GC Padron, JR Beal, X Chen, Y Wang, ...
Nature Communications 12 (1), 3815, 2021
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