Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules M Akeson, D Branton, JJ Kasianowicz, E Brandin, DW Deamer Biophysical journal 77 (6), 3227-3233, 1999 | 1214 | 1999 |
The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community M Jain, HE Olsen, B Paten, M Akeson Genome biology 17 (1), 1-11, 2016 | 1002 | 2016 |
Three decades of nanopore sequencing D Deamer, M Akeson, D Branton Nature biotechnology 34 (5), 518-524, 2016 | 698 | 2016 |
Improved data analysis for the MinION nanopore sequencer M Jain, IT Fiddes, KH Miga, HE Olsen, B Paten, M Akeson Nature methods 12 (4), 351-356, 2015 | 648 | 2015 |
Automated forward and reverse ratcheting of DNA in a nanopore at 5-Å precision GM Cherf, KR Lieberman, H Rashid, CE Lam, K Karplus, M Akeson Nature biotechnology 30 (4), 344-348, 2012 | 616 | 2012 |
Nanopores and nucleic acids: prospects for ultrarapid sequencing DW Deamer, M Akeson Trends in biotechnology 18 (4), 147-151, 2000 | 551 | 2000 |
Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel W Vercoutere, S Winters-Hilt, H Olsen, D Deamer, D Haussler, M Akeson Nature biotechnology 19 (3), 248-252, 2001 | 543 | 2001 |
Characterization of individual polymer molecules based on monomer-interface interactions R Baldarelli, D Branton, G Church, DW Deamer, M Akeson, J Kasianowicz US Patent 6,015,714, 2000 | 366 | 2000 |
Single-molecule analysis of DNA-protein complexes using nanopores B Hornblower, A Coombs, RD Whitaker, A Kolomeisky, SJ Picone, ... Nature Methods 4 (4), 315-317, 2007 | 341 | 2007 |
Unfoldase-mediated protein translocation through an α-hemolysin nanopore J Nivala, DB Marks, M Akeson Nature biotechnology 31 (3), 247-250, 2013 | 311 | 2013 |
Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymerase KR Lieberman, GM Cherf, MJ Doody, F Olasagasti, Y Kolodji, M Akeson Journal of the American Chemical Society 132 (50), 17961-17972, 2010 | 302 | 2010 |
Mapping DNA methylation with high-throughput nanopore sequencing AC Rand, M Jain, JM Eizenga, A Musselman-Brown, HE Olsen, M Akeson, ... Nature methods 14 (4), 411-413, 2017 | 300 | 2017 |
Nanopore long-read RNAseq reveals widespread transcriptional variation among the surface receptors of individual B cells A Byrne, AE Beaudin, HE Olsen, M Jain, C Cole, T Palmer, RM DuBois, ... Nature communications 8 (1), 1-11, 2017 | 282 | 2017 |
Nanopore native RNA sequencing of a human poly (A) transcriptome RE Workman, AD Tang, PS Tang, M Jain, JR Tyson, R Razaghi, ... Nature methods 16 (12), 1297-1305, 2019 | 277 | 2019 |
Sequence-specific detection of individual DNA polymerase complexes in real time using a nanopore S Benner, RJA Chen, NA Wilson, R Abu-Shumays, N Hurt, KR Lieberman, ... Nature nanotechnology 2 (11), 718-724, 2007 | 266 | 2007 |
Methods and apparatus for characterizing polynucleotides M Akeson, D Branton, DW Deamer, JR Sampson US Patent 7,238,485, 2007 | 262* | 2007 |
Nanopore sensors for nucleic acid analysis JJ Nakane, M Akeson, A Marziali Journal of Physics: Condensed Matter 15 (32), R1365, 2003 | 216 | 2003 |
New DNA sequencing methods A Marziali, M Akeson Annual review of biomedical engineering 3 (1), 195-223, 2001 | 209 | 2001 |
Replication of individual DNA molecules under electronic control using a protein nanopore F Olasagasti, KR Lieberman, S Benner, GM Cherf, JM Dahl, DW Deamer, ... Nature nanotechnology 5 (11), 798-806, 2010 | 201 | 2010 |
Discrimination among individual Watson–Crick base pairs at the termini of single DNA hairpin molecules WA Vercoutere, S Winters‐Hilt, VS DeGuzman, D Deamer, SE Ridino, ... Nucleic acids research 31 (4), 1311-1318, 2003 | 199 | 2003 |