Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA V Chandra, P Huang, Y Hamuro, S Raghuram, Y Wang, TP Burris, ... Nature 456 (7220), 350-356, 2008 | 918 | 2008 |
Bile acid metabolites control TH17 and Treg cell differentiation S Hang, D Paik, L Yao, E Kim, J Trinath, J Lu, S Ha, BN Nelson, SP Kelly, ... Nature 576 (7785), 143-148, 2019 | 788 | 2019 |
Structural determinants of nuclear receptor assembly on DNA direct repeats F Rastinejad, T Perlmann, RM Evans, PB Sigler Nature 375 (6528), 203-211, 1995 | 755 | 1995 |
Double chromodomains cooperate to recognize the methylated histone H3 tail JF Flanagan, LZ Mi, M Chruszcz, M Cymborowski, KL Clines, Y Kim, ... Nature 438 (7071), 1181-1185, 2005 | 694 | 2005 |
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ S Raghuram, KR Stayrook, P Huang, PM Rogers, AK Nosie, DB McClure, ... Nature structural & molecular biology 14 (12), 1207-1213, 2007 | 662 | 2007 |
Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics P Huang, V Chandra, F Rastinejad Annual review of physiology 72, 247-272, 2010 | 624 | 2010 |
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ... Nature 472 (7344), 486-490, 2011 | 594 | 2011 |
Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ... ACS chemical biology 11 (11), 3214-3225, 2016 | 438 | 2016 |
Nuclear-receptor interactions on DNA-response elements S Khorasanizadeh, F Rastinejad Trends in biochemical sciences 26 (6), 384-390, 2001 | 393 | 2001 |
Structural basis for bile acid binding and activation of the nuclear receptor FXR LZ Mi, S Devarakonda, JM Harp, Q Han, R Pellicciari, TM Willson, ... Molecular cell 11 (4), 1093-1100, 2003 | 341 | 2003 |
Structural integration in hypoxia-inducible factors D Wu, N Potluri, J Lu, Y Kim, F Rastinejad Nature 524 (7565), 303-308, 2015 | 310 | 2015 |
Tapinarof is a natural AhR agonist that resolves skin inflammation in mice and humans SH Smith, C Jayawickreme, DJ Rickard, E Nicodeme, T Bui, C Simmons, ... Journal of Investigative Dermatology 137 (10), 2110-2119, 2017 | 267 | 2017 |
Structure of the RXR–RAR DNA-binding complex on the retinoic acid response element DR1 F Rastinejad, T Wagner, Q Zhao, S Khorasanizadeh The EMBO journal 19 (5), 1045-1054, 2000 | 258 | 2000 |
Human gut bacteria produce ΤΗ17-modulating bile acid metabolites D Paik, L Yao, Y Zhang, S Bae, GD D’Agostino, M Zhang, E Kim, ... Nature 603 (7903), 907-912, 2022 | 245 | 2022 |
Vitamin D binding protein: a historic overview R Bouillon, F Schuit, L Antonio, F Rastinejad Frontiers in endocrinology 10, 484325, 2020 | 238 | 2020 |
Retinoid X receptor and its partners in the nuclear receptor family F Rastinejad Current opinion in structural biology 11 (1), 33-38, 2001 | 234 | 2001 |
DNA binding domains in diverse nuclear receptors function as nuclear export signals BE Black, JM Holaska, F Rastinejad, BM Paschal Current Biology 11 (22), 1749-1758, 2001 | 228 | 2001 |
Understanding nuclear receptor form and function using structural biology F Rastinejad, P Huang, V Chandra, S Khorasanizadeh Journal of molecular endocrinology 51 (3), T1-T21, 2013 | 220 | 2013 |
Identification of natural RORγ ligands that regulate the development of lymphoid cells FR Santori, P Huang, SA Van De Pavert, EF Douglass, DJ Leaver, ... Cell metabolism 21 (2), 286-298, 2015 | 219 | 2015 |
Multidomain integration in the structure of the HNF-4α nuclear receptor complex V Chandra, P Huang, N Potluri, D Wu, Y Kim, F Rastinejad Nature 495 (7441), 394-398, 2013 | 212 | 2013 |