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Fraydoon Rastinejad
Fraydoon Rastinejad
Professor, University of Oxford, Nuffield Department of Medicine, Target Discovery Institute
Verified email at ndm.ox.ac.uk - Homepage
Title
Cited by
Cited by
Year
Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA
V Chandra, P Huang, Y Hamuro, S Raghuram, Y Wang, TP Burris, ...
Nature 456 (7220), 350-356, 2008
9182008
Bile acid metabolites control TH17 and Treg cell differentiation
S Hang, D Paik, L Yao, E Kim, J Trinath, J Lu, S Ha, BN Nelson, SP Kelly, ...
Nature 576 (7785), 143-148, 2019
7882019
Structural determinants of nuclear receptor assembly on DNA direct repeats
F Rastinejad, T Perlmann, RM Evans, PB Sigler
Nature 375 (6528), 203-211, 1995
7551995
Double chromodomains cooperate to recognize the methylated histone H3 tail
JF Flanagan, LZ Mi, M Chruszcz, M Cymborowski, KL Clines, Y Kim, ...
Nature 438 (7071), 1181-1185, 2005
6942005
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ
S Raghuram, KR Stayrook, P Huang, PM Rogers, AK Nosie, DB McClure, ...
Nature structural & molecular biology 14 (12), 1207-1213, 2007
6622007
Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics
P Huang, V Chandra, F Rastinejad
Annual review of physiology 72, 247-272, 2010
6242010
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ...
Nature 472 (7344), 486-490, 2011
5942011
Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors
A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ...
ACS chemical biology 11 (11), 3214-3225, 2016
4382016
Nuclear-receptor interactions on DNA-response elements
S Khorasanizadeh, F Rastinejad
Trends in biochemical sciences 26 (6), 384-390, 2001
3932001
Structural basis for bile acid binding and activation of the nuclear receptor FXR
LZ Mi, S Devarakonda, JM Harp, Q Han, R Pellicciari, TM Willson, ...
Molecular cell 11 (4), 1093-1100, 2003
3412003
Structural integration in hypoxia-inducible factors
D Wu, N Potluri, J Lu, Y Kim, F Rastinejad
Nature 524 (7565), 303-308, 2015
3102015
Tapinarof is a natural AhR agonist that resolves skin inflammation in mice and humans
SH Smith, C Jayawickreme, DJ Rickard, E Nicodeme, T Bui, C Simmons, ...
Journal of Investigative Dermatology 137 (10), 2110-2119, 2017
2672017
Structure of the RXR–RAR DNA-binding complex on the retinoic acid response element DR1
F Rastinejad, T Wagner, Q Zhao, S Khorasanizadeh
The EMBO journal 19 (5), 1045-1054, 2000
2582000
Human gut bacteria produce ΤΗ17-modulating bile acid metabolites
D Paik, L Yao, Y Zhang, S Bae, GD D’Agostino, M Zhang, E Kim, ...
Nature 603 (7903), 907-912, 2022
2452022
Vitamin D binding protein: a historic overview
R Bouillon, F Schuit, L Antonio, F Rastinejad
Frontiers in endocrinology 10, 484325, 2020
2382020
Retinoid X receptor and its partners in the nuclear receptor family
F Rastinejad
Current opinion in structural biology 11 (1), 33-38, 2001
2342001
DNA binding domains in diverse nuclear receptors function as nuclear export signals
BE Black, JM Holaska, F Rastinejad, BM Paschal
Current Biology 11 (22), 1749-1758, 2001
2282001
Understanding nuclear receptor form and function using structural biology
F Rastinejad, P Huang, V Chandra, S Khorasanizadeh
Journal of molecular endocrinology 51 (3), T1-T21, 2013
2202013
Identification of natural RORγ ligands that regulate the development of lymphoid cells
FR Santori, P Huang, SA Van De Pavert, EF Douglass, DJ Leaver, ...
Cell metabolism 21 (2), 286-298, 2015
2192015
Multidomain integration in the structure of the HNF-4α nuclear receptor complex
V Chandra, P Huang, N Potluri, D Wu, Y Kim, F Rastinejad
Nature 495 (7441), 394-398, 2013
2122013
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