Roger L Williams

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	Wszystkie	Od 2019
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John E BurkeProfessor of Biochemistry and Microbiology, University of VictoriaZweryfikowany adres z uvic.ca
Glenn R. MassonUniversity of Dundee, School of MedicineZweryfikowany adres z dundee.ac.uk
Alex BerndtResearch Scientist MRC-LMBZweryfikowany adres z mrc-lmb.cam.ac.uk
Oscar VadasPostdoc at the Medical Research Council - Laboratory of Molecular Biology, Cambridge, UKZweryfikowany adres z unige.ch
Phillip HawkinsGroup Leader, Babraham InstituteZweryfikowany adres z babraham.ac.uk
Yohei OhashiLaboratory of Molecular Biology, Medical Research CouncilZweryfikowany adres z mrc-lmb.cam.ac.uk
Eddy ArnoldBoard of Governors and Distinguished Professor of Chemistry and Chemical Biology, Rutgers UniversityZweryfikowany adres z cabm.rutgers.edu
Dmitry VeprintsevProfessor of Molecular and Cellular Pharmacology, University of NottinghamZweryfikowany adres z nottingham.ac.uk
Jerónimo BravoConsejo Superior de Investigaciones CientíficasZweryfikowany adres z ibv.csic.es
Scott D EmrCornell UniversityZweryfikowany adres z cornell.edu
Marketa ZvelebilAssistant Professor in Cancer Informatics, ICRZweryfikowany adres z icr.ac.uk
Christopher M JohnsonMRC Laboratory of Molecular BiologyZweryfikowany adres z mrc-lmb.cam.ac.uk
Zachary KnightUCSF and HHMIZweryfikowany adres z ucsf.edu
Dom BaretićThe Dunn School, OxfordZweryfikowany adres z path.ox.ac.uk
Robert StahelinRetter Professor of Pharmacy, Purdue UniversityZweryfikowany adres z purdue.edu
Joseph J. FalkeDirector of Molecular Biophysics, Prof. of Chemistry & Biochemistry, CU BoulderZweryfikowany adres z colorado.edu
Hashem DboukZweryfikowany adres z phd.einstein.yu.edu
Chris TantilloWorld Health OrganizationZweryfikowany adres z who.int
Eli R. ZunderAssistant Professor, University of VirginiaZweryfikowany adres z virginia.edu
Robbie LoewithUniversity of GenevaZweryfikowany adres z unige.ch

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Roger L Williams

Group leader, Medical Research Council, Laboratory of Molecular Biology

Zweryfikowany adres z mrc-lmb.cam.ac.uk - Strona główna

structural biology escrt pi3k phosphoinositide PIKK


Tytuł Sortuj wg cytatów Sortuj wg roku Sortuj wg tytułu	Cytowane przez Cytowane przez	Rok
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹ DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021	11106	2021
Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine EH Walker, ME Pacold, O Perisic, L Stephens, PT Hawkins, MP Wymann, ... Molecular cell 6 (4), 909-919, 2000	1547	2000
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. A Jacobo-Molina, J Ding, RG Nanni, AD Clark Jr, X Lu, C Tantillo, ... Proceedings of the National Academy of Sciences 90 (13), 6320-6324, 1993	1523	1993
A pharmacological map of the PI3-K family defines a role for p110α in insulin signaling ZA Knight, B Gonzalez, ME Feldman, ER Zunder, DD Goldenberg, ... Cell 125 (4), 733-747, 2006	1419	2006
The emerging shape of the ESCRT machinery RL Williams, S Urbé Nature reviews Molecular cell biology 8 (5), 355-368, 2007	920	2007
Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase γ ME Pacold, S Suire, O Perisic, S Lara-Gonzalez, CT Davis, EH Walker, ... Cell 103 (6), 931-944, 2000	801	2000
Crystal structure of a mammalian phosphoinositide-specific phospholipase Cδ LO Essen, O Perisic, R Cheung, M Katan, RL Williams Nature 380 (6575), 595-602, 1996	727	1996
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ... Science 342 (6160), 866-871, 2013	667	2013
Structural insights into phosphoinositide 3-kinase catalysis and signalling EH Walker, O Perisic, C Ried, L Stephens, RL Williams Nature 402 (6759), 313-320, 1999	642	1999
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases B Apsel, JA Blair, B Gonzalez, TM Nazif, ME Feldman, B Aizenstein, ... Nature chemical biology 4 (11), 691, 2008	576	2008
Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit N Miled, Y Yan, WC Hon, O Perisic, M Zvelebil, Y Inbar, ... science 317 (5835), 239-242, 2007	475	2007
Binding of the PX domain of p47phox to phosphatidylinositol 3, 4‐bisphosphate and phosphatidic acid is masked by an intramolecular interaction D Karathanassis, RV Stahelin, J Bravo, O Perisic, CM Pacold, W Cho, ... The EMBO journal, 2002	386	2002
A role for the ESCRT system in cell division in archaea RY Samson, T Obita, SM Freund, RL Williams, SD Bell Science 322 (5908), 1710-1713, 2008	376	2008
The p110δ structure: mechanisms for selectivity and potency of new PI (3) K inhibitors A Berndt, S Miller, O Williams, DD Le, BT Houseman, JI Pacold, F Gorrec, ... Nature chemical biology 6 (2), 117-124, 2010	350	2010
The crystal structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate J Bravo, D Karathanassis, CM Pacold, ME Pacold, CD Ellson, ... Molecular cell 8 (4), 829-839, 2001	341	2001
Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4 T Obita, S Saksena, S Ghazi-Tabatabai, DJ Gill, O Perisic, SD Emr, ... Nature 449 (7163), 735-739, 2007	337	2007
Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2 O Perisic, S Fong, DE Lynch, M Bycroft, RL Williams Journal of Biological Chemistry 273 (3), 1596-1604, 1998	334	1998
Structural basis for activation and inhibition of class I phosphoinositide 3-kinases O Vadas, JE Burke, X Zhang, A Berndt, RL Williams Science signaling 4 (195), re2-re2, 2011	322	2011
ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes H Teo, DJ Gill, J Sun, O Perisic, DB Veprintsev, Y Vallis, SD Emr, ... Cell 125 (1), 99-111, 2006	316	2006
Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA) JE Burke, O Perisic, GR Masson, O Vadas, RL Williams Proceedings of the National Academy of Sciences 109 (38), 15259-15264, 2012	308	2012

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