| Global dynamics of proteins: bridging between structure and function I Bahar, TR Lezon, LW Yang, E Eyal Annual review of biophysics 39, 23-42, 2010 | 634 | 2010 |
| Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins I Bahar, TR Lezon, A Bakan, IH Shrivastava Chemical reviews 110 (3), 1463-1497, 2010 | 562 | 2010 |
| Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release Y Suofu, W Li, FG Jean-Alphonse, J Jia, NK Khattar, J Li, SV Baranov, ... Proceedings of the National Academy of Sciences 114 (38), E7997-E8006, 2017 | 398 | 2017 |
| Using the principle of entropy maximization to infer genetic interaction networks from gene expression patterns TR Lezon, JR Banavar, M Cieplak, A Maritan, NV Fedoroff Proceedings of the National Academy of Sciences 103 (50), 19033-19038, 2006 | 293 | 2006 |
| Evol and ProDy for bridging protein sequence evolution and structural dynamics A Bakan, A Dutta, W Mao, Y Liu, C Chennubhotla, TR Lezon, I Bahar Bioinformatics 30 (18), 2681-2683, 2014 | 211 | 2014 |
| Biologically relevant heterogeneity: metrics and practical insights A Gough, AM Stern, J Maier, T Lezon, TY Shun, C Chennubhotla, ... Slas Discovery: Advancing Life Sciences R&D 22 (3), 213-237, 2017 | 76 | 2017 |
| Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery AH Gough, N Chen, TY Shun, TR Lezon, RC Boltz, CE Reese, J Wagner, ... PloS one 9 (7), e102678, 2014 | 62 | 2014 |
| Constraints imposed by the membrane selectively guide the alternating access dynamics of the glutamate transporter GltPh TR Lezon, I Bahar Biophysical journal 102 (6), 1331-1340, 2012 | 49 | 2012 |
| Using entropy maximization to understand the determinants of structural dynamics beyond native contact topology TR Lezon, I Bahar PLoS computational biology 6 (6), e1000816, 2010 | 45 | 2010 |
| Global motions of the nuclear pore complex: insights from elastic network models TR Lezon, A Sali, I Bahar PLoS computational biology 5 (9), e1000496, 2009 | 39 | 2009 |
| Proteomic screening and lasso regression reveal differential signaling in insulin and insulin-like growth factor I (IGF1) pathways C Erdem, AM Nagle, AJ Casa, BC Litzenburger, Y Wang, DL Taylor, ... Molecular & Cellular Proteomics 15 (9), 3045-3057, 2016 | 29 | 2016 |
| Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers DM Spagnolo, R Gyanchandani, Y Al-Kofahi, AM Stern, TR Lezon, ... Journal of pathology informatics 7 (1), 47, 2016 | 28 | 2016 |
| Platform for quantitative evaluation of spatial intratumoral heterogeneity in multiplexed fluorescence images DM Spagnolo, Y Al-Kofahi, P Zhu, TR Lezon, A Gough, AM Stern, AV Lee, ... Cancer research 77 (21), e71-e74, 2017 | 26 | 2017 |
| High-content analysis with cellular and tissue systems biology: a bridge between cancer cell biology and tissue-based diagnostics A Gough, T Lezon, JR Faeder, C Chennubhotla, RF Murphy, ... The molecular basis of cancer, 369-392. e7, 2015 | 22 | 2015 |
| Elastic network models for biomolecular dynamics: theory and application to membrane proteins and viruses TR Lezon, IH Shrivastava, Z Yang, I Bahar Handbook on biological networks, 129-58, 2009 | 22 | 2009 |
| The origami of life TR Lezon, JR Banavar, A Maritan Journal of Physics: Condensed Matter 18 (3), 847, 2006 | 21 | 2006 |
| Connecting neuronal cell protective pathways and drug combinations in a Huntington’s disease model through the application of quantitative systems pharmacology F Pei, H Li, MJ Henderson, SA Titus, A Jadhav, A Simeonov, ... Scientific Reports 7 (1), 17803, 2017 | 19 | 2017 |
| Harnessing human microphysiology systems as key experimental models for quantitative systems pharmacology DL Taylor, A Gough, ME Schurdak, L Vernetti, CS Chennubhotla, ... Concepts and Principles of Pharmacology: 100 Years of the Handbook of …, 2019 | 18 | 2019 |
| Geometry of proteins: hydrogen bonding, sterics, and marginally compact tubes JR Banavar, M Cieplak, A Flammini, TX Hoang, RD Kamien, T Lezon, ... Physical Review E 73 (3), 031921, 2006 | 15 | 2006 |
| Predicting the effects of drug combinations using probabilistic matrix factorization R Nafshi, TR Lezon Frontiers in Bioinformatics 1, 708815, 2021 | 9 | 2021 |
