| Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders BR Bellenie, KMJ Cheung, A Varela, OA Pierrat, GW Collie, GM Box, ... Journal of Medicinal Chemistry 63 (8), 4047-4068, 2020 | 47 | 2020 |
| Ultrafast structural changes direct the first molecular events of vision T Gruhl, T Weinert, MJ Rodrigues, CJ Milne, G Ortolani, K Nass, E Nango, ... Nature 615 (7954), 939-944, 2023 | 42 | 2023 |
| Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis MJ Rodrigues, V Windeisen, Y Zhang, G Guédez, S Weber, M Strohmeier, ... Nature Chemical Biology, 2017 | 21 | 2017 |
| Optimizing shape complementarity enables the discovery of potent tricyclic BCL6 inhibitors OA Davis, KMJ Cheung, A Brennan, MG Lloyd, MJ Rodrigues, OA Pierrat, ... Journal of Medicinal Chemistry 65 (12), 8169-8190, 2022 | 12 | 2022 |
| Into deep water: Optimizing BCL6 inhibitors by growing into a solvated pocket MG Lloyd, R Huckvale, KMJ Cheung, MJ Rodrigues, GW Collie, ... Journal of Medicinal Chemistry 64 (23), 17079-17097, 2021 | 11 | 2021 |
| Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel DCA Barret, D Schuster, MJ Rodrigues, A Leitner, P Picotti, GFX Schertler, ... Proceedings of the National Academy of Sciences 120 (15), e2300309120, 2023 | 6 | 2023 |
| Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays OA Pierrat, M Liu, GW Collie, K Shetty, MJ Rodrigues, YV Le Bihan, ... Scientific Reports 12 (1), 18633, 2022 | 2 | 2022 |
| Correction of rhodopsin serial crystallography diffraction intensities for a lattice-translocation defect MJ Rodrigues, CM Casadei, T Weinert, V Panneels, GFX Schertler Acta Crystallographica Section D: Structural Biology 79 (3), 224-233, 2023 | 1 | 2023 |
| Cyclic peptide inhibitors stabilize Gq/11 heterotrimers J Mühle, MJ Rodrigues, J Alenfelder, L Jürgenliemke, R Guixà-González, ... bioRxiv, 2023.10. 24.563737, 2023 | 1 | 2023 |
| Graph‐based algorithms to dissect long‐distance water‐mediated H‐bond networks for conformational couplings in GPCRs É Bertalan, MJ Rodrigues, GFX Schertler, AN Bondar British Journal of Pharmacology, 2024 | | 2024 |
| A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus R Bolton, MM Machelett, J Stubbs, D Axford, N Caramello, L Catapano, ... Proceedings of the National Academy of Sciences 121 (12), e2308478121, 2024 | | 2024 |
| Active state structures of a bistable visual opsin bound to G proteins O Tejero, FK Pamula, M Koyanagi, T Nagata, P Afanasyev, I Das, X Deupi, ... bioRxiv, 2024.04. 09.588704, 2024 | | 2024 |
| Activating an invertebrate bistable opsin with the all-trans 6.11 retinal analogue MJ Rodrigues, O Tejero, J Muhle, FK Pamula, I Das, CJ Tsai, A Terakita, ... bioRxiv, 2024.04. 08.588240, 2024 | | 2024 |
| Trapping a novel intermediate of vitamin B6 biosynthesis in PLP synthase, using in crystallo spectroscopy M Rodrigues, N Giri, A Royant, Y Zhang, R Bolton, G Evans, S Ealick, ... Acta Crystallographica Section A: Foundations and Advances 78, a379-a379, 2022 | | 2022 |
| Trapping and structural characterisation of a covalent intermediate in vitamin B 6 biosynthesis catalysed by the Pdx1 PLP synthase MJ Rodrigues, N Giri, A Royant, Y Zhang, R Bolton, G Evans, SE Ealick, ... RSC Chemical Biology 3 (2), 227-230, 2022 | | 2022 |
| An investigation into the catalytic mechanism of vitamin B6 biosynthesis using x-ray crystallography and UV-Vis spectroscopy MJ Rodrigues University of Southampton, 2017 | | 2017 |
| MS06-2-3 Trapping a novel intermediate of vitamin B6 biosynthesis in PLP synthase, using in crystallo spectroscopy# MS06-2-3 M Rodrigues, N Giri, A Royant, Y Zhang, R Bolton, G Evans, S Ealick, ... Foundations of Crystallography, 0 | | |
Dr Ivo TewsLecturer in Structural Biology, University of SouthamptonVerified email at soton.ac.uk
